64168-08-7

Basic information

• Product Name: 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE
• Synonyms: 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE;N-Benzyl-4-(dimethylamino)piperidine;1-Benzyl-4-(dimethylamino)
• CAS NO: 64168-08-7
• Molecular Formula: C₁₄H₂₂N₂
• Molecular Weight: 218.33788
• Mol File: 64168-08-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE(64168-08-7)
• EPA Substance Registry System: 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE(64168-08-7)

Safety Data

• Hazardous Substances Data: 64168-08-7(Hazardous Substances Data)

Usage

General Description

1-Benzyl-4-dimethylaminopiperidine is a chemical compound with the formula C17H26N2. It is a piperidine derivative and a tertiary amine, containing a benzyl group and two methyl groups attached to the piperidine ring. 1-BENZYL-4-DIMETHYLAMINOPIPERIDINE is commonly used as a reagent in organic synthesis and pharmaceutical chemistry, where it can act as a catalyst or a building block for the synthesis of various molecules. It has also been found to have potential pharmacological properties, such as acting as a local anesthetic and as an inhibitor of voltage-gated sodium channels. However, it is important to handle and use this compound with caution due to its potential toxicity and health hazards.

Upstream product

• 24686-78-0 1-Benzoyl-4-piperidone 
• 27691-43-6 1-(benzylsulphanyl)-4-Nitrobenzene 
• 50533-97-6 dimethyl-piperidin-4-yl-amine 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 506-59-2 N,N-dimethylammonium chloride 
• 84157-05-1 phenyl(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 98-88-4 benzoyl chloride 
• 93865-36-2 (4-dimethylaminopiperidin-1-yl)phenylmethanone 
• 100-46-9 benzylamine 
• 50-00-0 formaldehyd 
• 50541-93-0 4-amino-1-benzylpiperidine 

Downstream Products

• 50533-97-6 dimethyl-piperidin-4-yl-amine 

Relevant articles and documents

Discriminating non-ylidic carbon-sulfur bond cleavages of sulfonium ylides for alkylation and arylation reactions

A sulfonium ylide participated alkylation and arylation under transition-metal free conditions is described. The disparate reaction pattern allowed the separate activation of non-ylidic S-alkyl and S-aryl bond. Under acidic conditions, sulfonium ylides serve as alkyl cation precursors which facilitate the alkylations. While under alkaline conditions, cleavage of non-ylidic S-aryl bond produces O-arylated compounds efficiently. The robustness of the protocols were established by the excellent compatibility of wide variety of substrates including carbohydrates.

2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION

A 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented by the generalformula (1): [Chemical formula 1] (1) or a pharmaceutically acceptable saltthereof. They are useful as a therapeutic/preventive agent for diabetes, diabeticnephropathy, or glomerulosclerosis.

Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: Structure-activity relation study of matrine-type alkaloids

We previously reported that (+)-matrine and (+)-allomatrine have antinociceptive properties mediated mainly through the activation of κ-opioid receptors. 1-Acyl-4-dialkylaminopiperidines were synthesized as the simplest derivatives of matrine, and the structure-activity relations were examined by the acetic acid-induced abdominal contraction test. The antinociceptive potencies of 1-alkyl-4-dialkylaminopiperidines were significantly lower than those of the corresponding 1-acyl-4- dialkylaminopiperidines. These findings suggest that the amide group of (+)-matrine is an essential functional group that influences antinociceptive potency.