642089-49-4

Upstream product

• 116585-12-7 2-((tert-butyldimethylsilyl)oxy)benzaldehyde 
• 536-74-3 phenylacetylene 
• 89-95-2 2-methyl-benzyl alcohol 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1542081-32-2 1-[2-(tert-butyldimethylsilyloxy)phenyl]-3-mercapto-3-phenylprop-2-en-1-one 
• 1404300-99-7 2-(2-benzylbenzofuran-3-yl)-1-phenylethanone 
• 1404300-87-3 2-benzyl-3-allylbenzofuran 
• 1404300-86-2 3-(2-benzylbenzofuran-3-yl)-1H-indole 
• 1404300-85-1 2-benzyl-3-(4-methoxyphenyl)benzofuran 
• 1404300-81-7 2-benzyl-3-(2,4,6-trimethoxyphenyl)benzofuran 
• 1404301-04-7 2-[3-phenyl-1-(2,4,6-trimethoxyphenyl)prop-2-ynyl]phenol 
• 37542-14-6 aurone 
• 525-82-6 FLAVONE 
• 4970-21-2 2-(diphenylmethylene)benzofuranone 
• 223511-19-1 1-[2-(tert-butyldimethylsilyloxy)phenyl]-3-phenylprop-2-yn-1-one 

Relevant academic research and scientific papers

Synthesis of 1,3-thioxoketones from salicylaldehyde

A method for the synthesis of monothiodibenzoylmethanes was developed. The method involves a reaction of potassium thioacetate with 1-(2-hydroxyphenyl)-3- phenylpropynone prepared from salicylaldehyde.

Access to 2,3-disubstituted benzofurans through one-pot acid-catalyzed nucleophilic substitution/TBAF-mediated oxacycloisomerization

An efficient synthetic strategy for the synthesis of diversely 2,3-disubstituted benzofurans is described. This method is based on the use of propargylic alcohols generated from TBS-protected ortho-hydroxy benzaldehydes as starting materials and allows a library of 2,3-disubstituted benzofurans to be built. The procedure consists of one-pot nucleophilic substitution, TBS-deprotection, and exo-dig cycloisomerization. Copyright

Synthesis of 2-(Diarylmethylene)-3-benzofuranones Promoted via Palladium-Catalyzed Reactions of Aryl iodides with 3-Aryl-1-(2-tert- butyldimethylsilyloxy)phenyl-2-propyn-1-ones

3-Substituted-1-(2-tert-butyldimethylsilyloxy)phenyl-2-propyn-1-ones were coupled with aryl iodides by using palladium as a catalyst in ambient MeOH solution and gave 2-(diarylmethylene)-3-benzofuranones in moderate to good yields.