6424-12-0

Usage

Uses

Used in Food Industry:
Raffinose Undecaacetate is used as a sweetener and stabilizer in various food products due to its sweetening properties and resistance to enzymatic reactions, which helps maintain product stability.
Used in Pharmaceutical Industry:
Raffinose Undecaacetate is used as a pharmaceutical ingredient for its potential health benefits, such as promoting healthy gut bacteria. Its sweetening and stabilizing properties also make it suitable for use in the development of pharmaceutical formulations.
Used in Flavoring Industry:
Raffinose Undecaacetate is used as a flavoring agent in the flavoring industry, leveraging its flavoring properties to enhance the taste and aroma of various products.

InChI:InChI=1/C40H54O27/c1-16(41)52-12-27-30(56-19(4)44)33(59-22(7)47)35(61-24(9)49)38(64-27)54-13-28-31(57-20(5)45)34(60-23(8)48)36(62-25(10)50)39(65-28)67-40(15-55-18(3)43)37(63-26(11)51)32(58-21(6)46)29(66-40)14-53-17(2)42/h27-39H,12-15H2,1-11H3

Upstream product

• 108-24-7 acetic anhydride 
• 512-69-6 D-raffinose 
• 75-36-5 acetyl chloride 
• 57-50-1 Sucrose 
• 7493-95-0 4-nitrophenyl α-D-galactoside 
• 536-11-8 D-melibiose 
• 6227-50-5 α-D-galactopyranosyl-(1->6)-O-α-D-glucopyranosyl-(1->2)-β-D-fructofuranoside pentahydrate 

Relevant academic research and scientific papers

GEL FORMULATIONS FOR IMPROVING IMMUNOTHERAPY

The present invention relates to a composition for use as controlled release of at least one active pharmaceutical ingredient that modulates an immunogenic response in a human or animal body, said composition comprising non-water soluble carbohydrates and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration.

GEL FORMULATIONS FOR LOCAL DRUG RELEASE

The present invention relates to a composition comprising non-water soluble carbohydrates, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, raffinose, glucosamine, galactosamine, lactosamine, or derivatives of disaccharides with at least two pyranose saccharide units, trisaccharides, tetrasaccharides, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration, for use as a medicament.

GEL FORMULATIONS FOR ENHANCING THE EFFECT OF RADIOTHERAPY

The present invention relates to a composition comprising: a. non-water soluble carbohydrates b. a contrast agent for imaging, wherein at least 60% of the contrast agent remains within 10 cm from the injection site after 24h, for use in local co-administration into a human or animal body, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration.

Acyl transfer reactions of carbohydrates, alcohols, phenols, thiols and thiophenols under green reaction conditions

Acyl transfer reactions of various carbohydrates, alcohols, phenols, thiols and thiophenols were achieved at room temperature in high yields and catalytic efficiency in the presence of methane sulfonic acid, a green organic acid, under solvent-free conditions over short time periods. The method is mild enough to allow acid labile substituents such as isopropylidene acetals and trityl ethers on the reacting substrates to be left completely unaffected. Esterification of free mono- and dicarboxylic acids such as acetic acid, cinnamic acid, sialic acid and tartaric acid with alcohols such as menthol, ethanol, methanol or propylene glycol has also been achieved efficiently at room temperature. A comparative study of the method with the silica-sulfuric acid is also reported.

Transglycosylations employing recombinant α- And β-galactosidases and novel donor substrates

Recombinant α- and β-galactosidases could be prepared in larger amounts for chemoenzymatic syntheses of glycosylated oligosaccharides relevant in nutrition approaches. α-Galactosidase RafA from Escherichia coli, another thermophilic α-galactosidase AgaB from Geobacillus stearothermophilus KVE39, and also a thermophilic β-galactosidase BglT from Thermus thermophilus TH 125 could be employed in α- and in β-glycosylations, respectively. With model structures as well as sucrose, isomaltitol, and isomaltulose the stereo- and regiospecificities were studied. Further, a number of modified donor structures with structural variation and different leaving groups were synthesized, employed, and compared to classical donors for these transglycosylations.

Efficient acylation and sulfation of carbohydrates using sulfamic acid, a mild, eco-friendly catalyst under organic solvent-free conditions

A fast and efficient acylation of carbohydrate derivatives and free sugars using a stoichiometric quantity of acylating agents in the presence of sulfamic acid, an environmentally benign catalyst, under organic solvent-free conditions is reported. Excellent yields in the selective acylation and sulfation of carbohydrate derivatives have also been achieved using sulfamic acid as the catalyst. The reaction is fast and the yields were excellent.

Acylation of carbohydrates over Al2O3: Preparation of partially and fully acylated carbohydrate derivatives and acetylated glycosyl chlorides

Selective and per-O-acylation of carbohydrate derivatives using acyl chlorides and Al2O3, a solid support reagent, is reported. This protocol does not require the addition of any base or activator. This methodology has been further extended to the selective acylation of carbohydrate diols and the one-pot preparation of acetylated glycosyl chlorides direct from free reducing sugars. The yields obtained in most of the cases are excellent.

Efficient acetylation of carbohydrates promoted by imidazole

An efficient per-O-acetylation of carbohydrate derivatives and unprotected reducing sugars promoted by imidazole is reported. The reaction conditions have been successfully employed to acetylate carbohydrate derivatives containing acid-susceptible functional groups. In most of the cases the yields obtained were excellent. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

HClO4-SiO2 catalyzed per-O-acetylation of carbohydrates

An efficient per-O-acetylation of carbohydrates catalyzed by HClO 4-SiO2 is reported using a stoichiometric quantity of acetic anhydride avoiding the use of pyridine and excess acetic anhydride under solvent-free conditions.

TRANS-ACIDOLYSIS PROCESS FOR THE PREPARATION OF SURFACE-ACTIVE CARBOHYDRATE FATTY-ACID ESTERS

The present invention relates to a low temperature, solvent-free trans-acidolysis process for preparing surface-active carbohydrate fatty-acid esters comprising the steps of reacting acylated carbohydrate with free fatty acid in the presence of acid catalyst, under reduced pressure, and without adding any solvent; decolorizing and separating the reaction mixture thus obtained into unreacted fatty acid and carbohydrate fatty-esters by solvent extraction and stage cooling. Hydroxyl groups on the carbohydrate fatty-esters are selectively librated by partial hydrolysis in the presence of an acid catalyst to modify HLB of product fatty-esters. The unreacted free fatty acids and unreacted carbohydrate substrates removed during purification are recycled to the starting reactant mixture.