64286-85-7Relevant articles and documents
Dual Catalytic Decarboxylative Allylations of α-Amino Acids and Their Divergent Mechanisms
Lang, Simon B.,O'Nele, Kathryn M.,Douglas, Justin T.,Tunge, Jon A.
supporting information, p. 18589 - 18593 (2016/01/25)
The room temperature radical decarboxylative allylation of N-protected α-amino acids and esters has been accomplished via a combination of palladium and photoredox catalysis to provide homoallylic amines. Mechanistic investigations revealed that the stability of the α-amino radical, which is formed by decarboxylation, dictates the predominant reaction pathway between competing mechanisms.
Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts
Zhong, Cheng,Wang, Yikai,Hung, Alvin W.,Schreiber, Stuart L.,Young, Damian W.
supporting information; experimental part, p. 5556 - 5559 (2011/12/05)
An intramolecular aza-Michael reaction with a Cbz carbamate and an enone is reported to result in 3,5-disubstituted nitrogen-containing heterocycles. Either cis or trans isomers were obtained selectively using chiral substrates and an achiral Pd (II) comp
A novel tert-butoxycarbonylation reagent: 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI)
Saito, Yukako,Ouchi, Hidekazu,Takahata, Hiroki
, p. 11599 - 11607 (2007/10/03)
The use of 1-tert-butoxy-2-tert-butoxycarbonyl-1,2-dihydroisoquinoline (BBDI) as a tert-butoxycarbonylation reagent for acidic proton-containing substrates such as phenols, aromatic and aliphatic amines hydrochlorides, and aromatic carboxylic acids in the absence of a base is described. The reactions proceed chemoselectively in high yield under mild conditions.