6437-67-8Relevant articles and documents
Synthesis of novel oxa-isosteres of spermidine and spermine
Lin, Paul Kong Thoo,Maguire, Nuala M.,Brown, Daniel M.
, p. 3605 - 3608 (1994)
3-Bromopropylamine hydrobromide reacts with N-hydroxyphthalimide in the presence of DBU to give, not the expected N-(3-aminopropyloxy)phthalimide, but N-(3-aminooxypropyl)-phthalimide, 6, formed by an unusual intramolecular rearrangement. Coupling of the pentamethyl-chroman-6-sulphonyl (Pmc) derivatives of 9 and 13 with N-Bpoc-aminopropanol affords a differentially protected 6-oxaspermidine 10 and 6,9-dioxaspermine 14 respectively from which the protecting groups are removed independently.
A highly efficient strategy for modification of proteins at the C terminus
Yi, Long,Sun, Hongyan,Wu, Yao-Wen,Triola, Gemma,Waldmann, Herbert,Goody, Roger S.
, p. 9417 - 9421 (2010)
A new linker: In a facile, chemoselective, and potentially general method for protein modification at the C terminus oxyamino-modified proteins obtained from protein thioesters react rapidly with ketones under mild conditions. This strategy was used for fluorescence labeling, for example with modified coumarin and fluorescein (see scheme). Copyright
Uracil-directed ligand tethering: An efficient strategy for uracil DNA glycosylase (UNG) inhibitor development
Jiang, Yu Lin,Krosky, Daniel J.,Seiple, Lauren,Stivers, James T.
, p. 17412 - 17420 (2005)
Uracil DNA glycosylase (UNG) is an important DNA repair enzyme that recognizes and excises uracil bases in DNA using an extrahelical recognition mechanism. It is emerging as a desirable target for small-molecule inhibitors given its key role in a wide ran
A family of salamo-type trinuclear Co(II) and Ni(II) complexes: Structural characterization, Hirshfeld surface analysis and fluorescent properties
Dong, Wen Kui,Li, Peng,Li, Shi-Zhen,Wei, Yu-Xin
, (2021)
Three trinuclear complexes, [{CoL(MeOH)(μ-OAc)}2Co] (1), [{CoL(EtOH)(μ-OAc)}2Co]·2CH3CH2OH (2) and [{NiL(MeOH)(μ-OAc)}2Ni]·2CH3OH (3) have been successfully synthesized by wet-chemical meth
Studying anion-dependent paradoxically fluorescent Cu(II) complexes bearing a pyridine-decorated tetradentate half-salamo-like ligand
Dong, Wen-Kui,Han, Xiu-Juan,Li, Ruo-Yu,Yue, Yong-Ning,Zhang, Yang
, (2021/10/12)
A new pyridine-decorated half-salamo-like ligand (HL) was designed and synthesized by a one-pot method. Based on this ligand, the single crystals of three anion-dependent Cu(II) complexes [Cu(L)Cl]·CH3OH (1), [Cu(L)Br] (2) and [Cu(L)(NO3/
Sequential multiple-target chemosensor: Co2+, Cu2+, PPi, and HSˉ discrimination by a bis(half-salamo)-type probe
Liu, Guo-Hua,Li, Mei,Li, Li-Li,Bian, Ruo-Nan,Dong, Wen-Kui
, p. 124 - 132 (2021/12/22)
A bis(half-salamo)-type chemosensor LPBHS based on phenanthroline, which can identify multiple targets continuously, was synthesized. The chemosensor LPBHS utilizes the N3O cavities to combine with metal cations, and further identify the anions after the complexes have been formed. The chemosensor LPBHS has an O-phenanthroline unit with excellent luminescence, so that the strong fluorescence of the chemosensor LPBHS can be observed under 365 nm UV light. The quenching of luminescence occurs after the introduction of Cu2+ and Co2+ into the chemosensor LPBHS, which can be identified in natural light by observing the change in color of the solution with the naked eye. The LPBHS-Cu2+ complex further recognizes HSˉ and PPi (pyrophosphoric acid), and strong luminescence are also observed under UV light after the addition of HSˉ and PPi to LPBHS-Cu2+. HSˉ and PPi can also be identified by the change in color of the solution under natural light with the naked eye. Using the strong fluorescence emission of LPBHS, a test strip was developed to detect Cu2+ and Co2+ rapidly, and the quenching of fluorescence was clearly observed under UV light. HSˉ and PPi can be further identified by the phenomenon of fluorescence recovery after Cu2+ detection on the test strip.
