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[[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)]], also known as ZnTMPyP, is a synthetic zinc complex of porphyrin. It is characterized by a zinc ion coordinated with a porphyrin ligand, which gives it unique structural and functional properties. ZnTMPyP has been the focus of research due to its potential applications in various fields, particularly in medicine and materials science.

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  • 64466-25-7 Structure
  • Basic information

    1. Product Name: [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)]
    2. Synonyms: [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)]
    3. CAS NO:64466-25-7
    4. Molecular Formula:
    5. Molecular Weight: 910.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 64466-25-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)](CAS DataBase Reference)
    10. NIST Chemistry Reference: [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)](64466-25-7)
    11. EPA Substance Registry System: [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)](64466-25-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 64466-25-7(Hazardous Substances Data)

64466-25-7 Usage

Uses

Used in Photodynamic Therapy:
ZnTMPyP is used as a photosensitizing agent for photodynamic therapy (PDT) in the treatment of cancer. [[μ-5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrinato(2-)]zinc(II)]'s ability to absorb light and generate reactive oxygen species (ROS) makes it effective in targeting and killing cancer cells upon light activation. This selective destruction of cancerous cells with minimal damage to surrounding healthy tissue is a significant advantage of PDT.
Used in Antioxidant Applications:
ZnTMPyP is utilized as an antioxidant, protecting cells and tissues from oxidative stress and damage caused by reactive oxygen species. Its strong antioxidant properties make it a potential candidate for the prevention and treatment of various diseases and conditions associated with oxidative stress, such as neurodegenerative disorders and cardiovascular diseases.
Used in Antibacterial Applications:
ZnTMPyP has been investigated for its antibacterial properties, making it a potential candidate for the development of new antimicrobial agents. Its ability to disrupt bacterial cell membranes and inhibit essential cellular processes can contribute to the fight against antibiotic-resistant bacteria.
Used in Materials Science:
The unique structure and properties of ZnTMPyP make it an interesting compound for research in materials science. Its potential applications in the development of new materials with specific optical, electronic, or magnetic properties are currently being explored.

Check Digit Verification of cas no

The CAS Registry Mumber 64466-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,6 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 64466-25:
(7*6)+(6*4)+(5*4)+(4*6)+(3*6)+(2*2)+(1*5)=137
137 % 10 = 7
So 64466-25-7 is a valid CAS Registry Number.

64466-25-7Relevant articles and documents

Photophysical properties and photodynamic therapy activity of a meso-tetra(4-carboxyphenyl)porphyrin tetramethyl ester-graphene quantum dot conjugate

Managa, Muthumuni,Ngoy, Bokolombe Pitchou,Nyokong, Tebello

, p. 4518 - 4524 (2019)

Novel meso-tetra(4-carboxyphenyl)porphyrin tetramethyl ester metal derivatives were synthesised and characterized. These derivatives were interacted with graphene quantum dots (GDQs). Spectroscopic evidence that was obtained showed that the resultant conjugates were stable due to the strong π-π stacking interaction between the GQDs and the porphyrins. The fluorescence and singlet oxygen generating behaviour of the porphyrins and the nanoconjugates were investigated following incorporation. The dark toxicity and photodynamic therapy activities of the porphyrins and the nanoconjugates were successfully studied using MCF-7 breast cancer cells. Cell viability for the dark toxicity was more than 90% for all complexes. The PDT activities at the highest concentration of 120 μg ml?1 showed a decrease in cell viability down to 15.2% for the GaClTMPP-GQDs.

Coupling of a new porphyrin photosensitizer and cobaloxime cocatalyst for highly efficient photocatalytic H2evolution

Bodedla, Govardhana Babu,Wong, Wai-Yeung,Zhu, Xunjin

supporting information, p. 20645 - 20652 (2021/09/28)

Photocatalytic hydrogen evolution (PHE) is a promising strategy to produce environmentally friendly clean energy with the use of solar power and water. For this, developing an efficient and noble metal free photocatalytic system (PS) comprising high light

H2S-Activable MOF Nanoparticle Photosensitizer for Effective Photodynamic Therapy against Cancer with Controllable Singlet-Oxygen Release

Ma, Yu,Li, Xiangyuan,Li, Aijie,Yang, Peng,Zhang, Caiyun,Tang, Bo

, p. 13752 - 13756 (2017/10/07)

Photodynamic therapy (PDT) has emerged as an important minimally invasive tumor treatment technology. The search for an effective photosensitizer to realize selective cancer treatment has become one of the major foci in recent developments of PDT technolo

ORGANIC DYE COMPLEX AND MANUFACTURING METHOD THEREFOR

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Paragraph 0194-0195, (2018/10/03)

PROBLEM TO BE SOLVED: To provide an organic dye complex having a wider area of absorption wavelengths, especially a wider area of absorption wavelengths in a near-infrared region. SOLUTION: There is provided a composite of a specific phthalocyanine derivative and a porphyrin derivative having a structure of the formula (2). In the formula (2), A, B, C and D represent each independently a hydrogen atom, a halogen atom or a monovalent organic group, at least two of the A to D are substituted or unsubstituted aryl or substituted or unsubstituted heteroaryl, M2 represents at least one atom or atom group that may bind with porphyrin. COPYRIGHT: (C)2015,JPO&INPIT

Two new self-assemblies of two zinc porphyrin with isonicotinic acid by metal-ligand axial coordination and their applications in supramolecular solar cell

Cao, Jing,Liu, Jia-Cheng,Chen, Li-Wei,Li, Ren-Zhi,Jin, Neng-Zhi

supporting information, p. 3851 - 3854 (2013/07/11)

Two new self-assemblies based on two zinc porphyrins substituted at the meso-positions with different donor units (denoted as ZnP1 and ZnP2) and isonicotinic acid (A) by metal-ligand axial coordination have been designed and immobilized on the double-laye

Change in supramolecular networks through in situ esterification of porphyrins

Chen, Wentong,Fukuzumi, Shunichi

, p. 5494 - 5505 (2010/06/15)

A series of porphyrins, M[TCPP-Et4] [M = Zn (1), Cu (2), and Ni (3) Et = CH2CH3; TCPP = meso-tetra(4-carboxyphenyl) porphyrin], M[TCPP-Me4] [M = Zn (4), Cu (S), and Co (6); Me = CH 3], and two nonmeta

Tetrachelate porphyrin chromophores for metal oxide semiconductor sensitization: Effect of the spacer length and anchoring group position

Rochford, Jonathan,Chu, Dorothy,Hagfeldt, Anders,Galoppini, Elena

, p. 4655 - 4665 (2007/10/03)

Four Zn(II)-tetra(carboxyphenyl)porphyrins in solution and bound to metal oxide (TiO2, ZnO, and ZrO2) nanoparticle films were studied to determine the effect of the spacer length and anchoring group position (para or meta) on their b

Clathrate solvates of tetrakis(4-methoxycarbonylphenyl)porphyrin and its zinc(II)-pyridine complex, in which the porphyrin host structures are stabilized by porphyrin-porphyrin stacking and C-H...O attractions

Muniappan, Sankar,Liptsman, Sophia,Goldberg, Israel

, p. m140-m143 (2007/10/03)

Tetrakis(4-methoxycarbonylphenyl)porphyrin, or tetramethyl 4,4′,4″,4?-porphyrin-5,10,15,20-tetrabenzoate, crystallizes as a nitrobenzene 1.9-solvate, C52H38N4O 8·1.9C6H5NO2, (I).

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