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Benzenesulfonamide, N-(2-chloroethyl)-, also known as Chlorambucil, is an organic compound with the chemical formula C8H8ClNO2S. It is a white crystalline solid that is soluble in water and various organic solvents. Chlorambucil is primarily used as an anticancer drug, specifically as an alkylating agent, which works by cross-linking DNA strands and inhibiting DNA synthesis, ultimately leading to cell death. It is commonly prescribed for the treatment of chronic lymphocytic leukemia, Hodgkin's lymphoma, and other malignancies. The compound is also used in veterinary medicine for the treatment of certain types of cancer in animals. Due to its potential side effects and toxicity, it is classified as a hazardous substance and requires careful handling and disposal.

6453-86-7

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6453-86-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6453-86-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,5 and 3 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6453-86:
(6*6)+(5*4)+(4*5)+(3*3)+(2*8)+(1*6)=107
107 % 10 = 7
So 6453-86-7 is a valid CAS Registry Number.

6453-86-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2-chloroethyl)benzenesulfonamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6453-86-7 SDS

6453-86-7Downstream Products

6453-86-7Relevant academic research and scientific papers

Synthesis and bioevaluation of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety

Thuan, Nguyen Thi,Dung, Do Thi Mai,Que, Do Nguyet,Dung, Phan Thi Phuong,Vu, Tran Khac,Hahn, Hyunggu,Han, Byung Woo,Kim, Youngsoo,Han, Sang-Bae,Nam, Nguyen-Hai

, p. 3803 - 3812 (2015/10/06)

Two series of new 5-benzylidenethiazolidine-2,4-diones bearing benzenesulfonamide moiety were designed and synthesized. The synthesized compounds were evaluated for several biological activities, including cytotoxicity, histone deacetylation, and protein

Sulfonamide herbicide antidote compositions and method of use

-

, (2008/06/13)

Herbicidal compositions consisting of an active herbicidal compound and an antidote therefor and the methods of use of the herbicide compositions are described herein. The antidote compound corresponds to the formula STR1 wherein R1 can be sele

Process for producing sulfonylamides

-

, (2008/06/13)

Sulfonylamide derivatives of the formula, wherein R is an alkyl or a phenyl group, which are particularly useful for the production of photographic chemicals, are prepared by the reaction between a sulfonylhalide of the formula, wherein R is as defined above, and X is chlorine or bromine, and 2-chloroethylamine or its salt, which is prepared by the chlorination of monoethanolamine with thionylchloride.

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