10302-15-5 Usage
General Description
1-(phenylsulphonyl)aziridine is a chemical compound containing an aziridine ring with a phenylsulphonyl group attached to it. It is a highly reactive and versatile intermediate in organic synthesis, commonly used in the preparation of various pharmaceuticals, agrochemicals, and fine chemicals. The presence of the phenylsulphonyl group makes 1-(phenylsulphonyl)aziridine an effective precursor for the introduction of a sulphonyl group into organic molecules. 1-(phenylsulphonyl)aziridine also exhibits potential for use as a reagent in asymmetric synthesis and as a building block for the construction of complex organic molecules. However, it is important to handle 1-(phenylsulphonyl)aziridine with caution, as it can be hazardous if not properly handled and stored.
Check Digit Verification of cas no
The CAS Registry Mumber 10302-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,0 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10302-15:
(7*1)+(6*0)+(5*3)+(4*0)+(3*2)+(2*1)+(1*5)=35
35 % 10 = 5
So 10302-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2S/c10-12(11,9-6-7-9)8-4-2-1-3-5-8/h1-5H,6-7H2
10302-15-5Relevant articles and documents
Synthesis of thiazolidine-thiones, imino-thiazolidines and oxazolidines: Via the base promoted cyclisation of epoxy-sulfonamides and heterocumulenes
Anitha, Mandala,Swamy, K. C. Kumara
, p. 402 - 413 (2018)
Epoxy-sulfonamides react with heterocumulenes (carbon disulfide/isothiocyanates/isocyanates) in the presence of a base to afford ring expansion products in good to high yields with excellent regioselectivity. N-(2-Bromoethyl)-sulfonamides can also be employed as substrates. This reaction proceeds through a 5-exo-tet pathway without forming aziridine intermediates.
Synthesis of indolines: Via a palladium/norbornene-catalyzed reaction of aziridines with aryl iodides
Liu, Ce,Liang, Yujie,Zheng, Nian,Zhang, Bo-Sheng,Feng, Yuan,Bi, Siwei,Liang, Yong-Min
supporting information, p. 3407 - 3410 (2018/04/05)
A Pd- and norbornene-catalyzed domino procedure has been developed to synthesize indoline compounds. This reaction provides efficient access to indolines by employing aryl iodides with aziridines as new electrophiles. The transformation is scalable and tolerates a range of functional groups.
