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N-(2-bromoethyl)benzenesulfonamide, also known as 2-Bromoethylbenzenesulfonamide, is a chemical compound that serves as an intermediate in the synthesis of pharmaceuticals and pesticides. It is a white solid with a molecular weight of 255.09 g/mol and is soluble in organic solvents. N-(2-bromoethyl)benzenesulfonamide is recognized for its role as a sulfonamide, a class of compounds that are commonly used as antibacterial agents and for treating various diseases. Due to its potential harmful effects if ingested, inhaled, or comes into contact with the skin, it is crucial to handle N-(2-bromoethyl)benzenesulfonamide with care and to use protective equipment during its manipulation.

6453-88-9

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6453-88-9 Usage

Uses

Used in Pharmaceutical Industry:
N-(2-bromoethyl)benzenesulfonamide is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its role as a sulfonamide allows it to contribute to the development of antibacterial agents and treatments for a range of diseases.
Used in Pesticide Industry:
In the pesticide industry, N-(2-bromoethyl)benzenesulfonamide is utilized as an intermediate in the production of pesticides. Its chemical properties make it a valuable component in creating effective pest control solutions.

Check Digit Verification of cas no

The CAS Registry Mumber 6453-88-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,5 and 3 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6453-88:
(6*6)+(5*4)+(4*5)+(3*3)+(2*8)+(1*8)=109
109 % 10 = 9
So 6453-88-9 is a valid CAS Registry Number.

6453-88-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(2-bromoethyl)benzenesulfonamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6453-88-9 SDS

6453-88-9Relevant articles and documents

PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR DISEASES ASSOCIATED WITH AMPA RECEPTORS

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Paragraph 0042; 0061; 0062, (2019/11/28)

This prophylactic and/or therapeutic agent for diseases associated with AMPA receptors contains a compound represented by formula (I), or a pharmaceutically acceptable salt or solvate thereof. (In the formula, A and Z independently represent CO, SO or SO

Solvent interception, heterocyclization and desilylation upon NBS-induced sulfamidation of trimethyl(vinyl)silane

Astakhova, Vera V.,Moskalik, Mikhail Yu.,Shainyan, Bagrat A.

, p. 7927 - 7937 (2019/09/06)

The reaction of trimethyl(vinyl)silane with sulfonamides in the presence of N-bromosuccinimide was shown to proceed regioselectively in methylene chloride under mild conditions and led to the products of bromosulfamidation in up to 88% yield. The obtained adducts undergo base-promoted dehydrobromination to give 2-trimethylsilyl-N-sulfonyl aziridines in a close to quantitative yield. In the reaction with trifluoromethanesulfonamide in acetonitrile or tetrahydrofuran, the Ritter-type (solvent-interception) products were obtained and converted to 1-triflyl-2-methyl-5-(trimethylsilyl)-2-imidazoline or 4-triflyl-3-(trimethylsilyl)-1,4-oxazocane in almost quantitative yield.

In vivo AMPA receptors in the brain imaging method of primates, program, and screening method

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Paragraph 0099, (2018/06/30)

This imaging method of AMPA receptors in the brain of primate organisms involves a step in which a substance which is administered to the primate organism and which selectively bonds to AMPA receptors in the brain of the primate organism and has a radiola

In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase

Bassetto, Marcella,Leyssen, Pieter,Neyts, Johan,Yerukhimovich, Mark M.,Frick, David N.,Courtney-Smith, Matthew,Brancale, Andrea

supporting information, p. 1115 - 1131 (2016/11/09)

A structure-based virtual screening of commercial compounds was carried out on the HCV NS3 helicase structure, with the aim to identify novel inhibitors of HCV replication. Among a selection of 13 commercial structures, one compound was found to inhibit the subgenomic HCV replicon in the low micromolar range. Different series of new piperazine-based analogues were designed and synthesised, and among them, several novel structures exhibited antiviral activity in the HCV replicon assay. Some of the new compounds were also found to inhibit HCV NS3 helicase function in?vitro, and one directly bound NS3 with a dissociation constant of 570?±?270?nM.

OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES 2

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Page/Page column 46, (2008/12/08)

Compounds of formula (I): wherein A, X, R1, R2, R3, R4, R5, R6 and R8 are as defined in the Specification are useful in the treatment of diseases where enhanced M3 receptor activ

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