645397-11-1Relevant academic research and scientific papers
2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonists
Chantigny, Yves A.,Murray, John C.,Kleinman, Edward F.,Robinson, Ralph P.,Plotkin, Michael A.,Reese, Matthew R.,Buckbinder, Leonard,McNiff, Patricia A.,Millham, Michele L.,Schaefer, Jean F.,Abramov, Yuriy A.,Bordner, Jon
, p. 2658 - 2677 (2015/04/14)
A significant improvement in agonist activity of the previously described 2-aryloctahydrophenanthrene-2,3,7-triol series of dissociated glucocorticoid receptor agonists (DAGRs) was achieved by modifying the substitution at C3 from (S)-3-hydroxy to (R)-3-h
MODULATORS OF THE GLUCOCORTICOID RECEPTOR
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Page 93, (2008/06/13)
The present invention provides compounds of the formula wherein A is of the formula and X, Y, n, R1-R25 are as described in the specification which are modulators of the glucocorticoid receptor and are thus useful for the treatment o
