645396-79-8

Basic information

• Product Name: (3E,4aR,10aR)-3-benzylidene-4a-ethyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one
• Synonyms: (3E,4aR,10aR)-3-benzylidene-4a-ethyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one
• CAS NO: 645396-79-8
• Molecular Weight: 332.442
• Mol File: 645396-79-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3E,4aR,10aR)-3-benzylidene-4a-ethyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E,4aR,10aR)-3-benzylidene-4a-ethyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one(645396-79-8)
• EPA Substance Registry System: (3E,4aR,10aR)-3-benzylidene-4a-ethyl-7-hydroxy-3,4,4a,9,10,10a-hexahydro-1H-phenanthren-2-one(645396-79-8)

Safety Data

• Hazardous Substances Data: 645396-79-8(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 

Downstream Products

• 645397-04-2 (3′E,4a′R,10a′R)-3′-benzylidene-4a′-ethyl-3′,4′,4a′,9′,10′,10a′-hexahydro-1′H-spiro[[1,3]dioxolane-2,2′-phenanthren]-7′-ol 
• 645396-80-1 (2S,3E,4aR,10aR)-3-benzylidene-4a-ethyl-2-phenyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol 
• 645397-05-3 (3′E,4a′R,10a′R)-3′-benzylidene-4a′-ethyl-3′,4′,4a′,9′,10′,10a′-hexahydro-1′H-spiro[[1,3]dioxolane-2,2′-phenanthrene]-7′-yl 4-nitrobenzoate 
• 645397-11-1 (4bR,7S,8aR,E)-6-benzylidene-4b-ethyl-7-hydroxy-7-(pyridin-2-yl)-4b,5,6,7,8,8a,9,10-octahydrophenanthren-2-yl 4-nitrobenzoate 
• 645397-10-0 (2S,4aR,10aR,E)-3-benzylidene-4a-ethyl-2-(pyridin-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-2,7-diol 

Relevant articles and documents

2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonists

A significant improvement in agonist activity of the previously described 2-aryloctahydrophenanthrene-2,3,7-triol series of dissociated glucocorticoid receptor agonists (DAGRs) was achieved by modifying the substitution at C3 from (S)-3-hydroxy to (R)-3-h