6460-81-7

Usage

InChI:InChI=1/C12H13NO5/c14-10(15)7-6-9(12(17)18)13-11(16)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,16)(H,14,15)(H,17,18)

Upstream product

• 623-11-0 1-methyl-4-nitrosobenzene 
• 2584-66-9 N-thiobenzoyl-L-glutamic acid 
• 7722-84-1 dihydrogen peroxide 
• 3551-51-7 N-(cyclopent-2-en-1-yl)-benzamide 
• 617-65-2 Glutamic acid 
• 98-88-4 benzoyl chloride 

Downstream Products

• 56-86-0 L-glutamic acid 
• 6094-36-6 N-benzoyl-L-glutamic acid 
• 58094-18-1 N-benzoyl-D-glutamic acid 
• 106270-21-7 4-benzoylamino-5-oxo-hexanoic acid 
• 91569-94-7 N-benzoyl-DL-glutamic acid-anhydride 
• 6893-26-1 D-Glutamic acid 
• 617-65-2 Glutamic acid 

Relevant academic research and scientific papers

Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists

A new series of 1,3-dioxane-2-carboxylic acid derivatives was synthesized and evaluated for agonist activity at human peroxisome proliferator-activated receptor (PPAR) subtypes. Structure-activity relationship studies led to the identification of 2-methyl-c-5-[4-(5-methyl-2-phenyl-1,3-oxazol-4-yl)butyl]-1,3-dioxane-r-2-carboxylic acid 4b as a potent PPARα agonist with high subtype selectivity at human receptor subtypes. This compound exhibited a substantial hypolipidemic effect in type 2 diabetic KK-Ay mice.

Beauveria bassiana ATCC 7159 contains an L-specific α-amino acid benzamidase

Biotransformation of a series of racemic N-benzoyl α-amino acids by the fungus Beauveria bassiana ATCC 7159 results in isolation of the corresponding D-amino acid benzamides in high enantiomeric purity and yield.

Asymmetric Catalysis by Vitamin B12: The Isomerization of Achiral Aziridines to Optically Active Allylic Amines

Achiral N-acylaziridines are isomerized to optically active N-acyl-allylamines in ee's of up to 95percent by catalytic amounts of cob(I)alamin in MeOH.

Composition containing a penem or carbapenem antibiotic

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.