64600-18-6

Basic information

• Product Name: Methanone, [1,1'-biphenyl]-4-yl(2-phenylcyclopropyl)-, trans-
• CAS NO: 64600-18-6
• Molecular Formula: C22H18O
• Molecular Weight: 298.384
• Mol File: 64600-18-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methanone, [1,1'-biphenyl]-4-yl(2-phenylcyclopropyl)-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [1,1'-biphenyl]-4-yl(2-phenylcyclopropyl)-, trans-(64600-18-6)
• EPA Substance Registry System: Methanone, [1,1'-biphenyl]-4-yl(2-phenylcyclopropyl)-, trans-(64600-18-6)

Safety Data

• Hazardous Substances Data: 64600-18-6(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 61668-23-3 2-diazo-1-biphenyl-4-yl-ethanone 
• 2453-44-3 3-Phenyl-2-propen-1-one 
• 1774-47-6 trimethylsulfoxonium iodide 
• 100-52-7 benzaldehyde 
• 92-91-1 biphenyl-4-acetaldehyde 

Relevant articles and documents

Rh(II)-Catalyzed Nitrene-Transfer [5 + 1] Cycloadditions of Aryl-Substituted Vinylcyclopropanes

Formal [5 + 1] cycloadditions between aryl-substituted vinylcyclopropanes and nitrenoid precursors are reported. The method, which employs Rh2(esp)2 as a catalyst, leads to the highly regioselective formation of substituted tetrahydropyridines. Preliminary mechanistic studies support a stepwise, polar mechanism enabled by the previously observed Lewis acidity of Rh-nitrenoids. Overall, this work expands the application of nitrene-transfer cycloaddition, a relatively underexplored approach to heterocycle synthesis, to the formation of six-membered rings.