646057-83-2

Upstream product

• 35661-39-3 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine 
• 71989-23-6 Fmoc-Ile-OH 
• 132388-59-1 L-Asn(Trt) 
• 646057-74-1 2(S)-2-[(3R,4S,5R)-5-benzyloxy-3-(fluorenyloxycarbonylamino)-4-hydroxy-2-oxo-1-piperidinyl]isohexanoic acid 
• 646057-70-7 (3S,4S,5R)-5-benzyloxy-N-[(1S)-1-(tert-butoxycarbonyl)-3-methylbutyl]-3-(9-fluorenylmethoxycarbonylamino)-4-hydroxypiperidin-2-one 
• 239784-28-2 (3S,4S,5R)-3-amino-5-benzyloxy-N-[(1S)-1-(tert-butoxycarbonyl)-3-methylbutyl]-4-hydroxypiperidin-2-one 

Downstream Products

• 646057-84-3 benzyl-ψ-stylostatin 

Relevant academic research and scientific papers

Constrained Derivatives of Stylostatin 1. 1. Synthesis and Biological Evaluation as Potential Anticancer Agents

Hydroxyaminolactams have been used as constrained surrogates of the Ser-Leu dipeptide in the synthesis of analogues of the cycloheptapeptide stylostatin 1 (2). The rate of cyclization through formation of the Ile-Pro amide bond allowed us to prove that th