64608-66-8

Usage

Uses

Used in Pharmaceutical Applications:
1-METHYL-3,4-DIHYDROPYRROLO[1,2-A]-PYRAZINE is used as a pharmaceutical compound for its potential therapeutic effects. Its psychoactive properties have been investigated for their potential role in treating mood disorders and neurological conditions, making it a candidate for further research and development in the pharmaceutical industry.
Used in Toxicological Research:
1-METHYL-3,4-DIHYDROPYRROLO[1,2-A]-PYRAZINE is used as a subject of toxicological research to study its potential role as a carcinogen and mutagen. Understanding its effects on human health can contribute to the development of safer compounds and inform regulations regarding its presence in consumer products, such as tobacco smoke.
Used in Chemical Analysis:
1-METHYL-3,4-DIHYDROPYRROLO[1,2-A]-PYRAZINE is used as a chemical marker in the analysis of various biological samples, including plant and fungal extracts. Its presence can provide insights into the composition and potential health effects of these sources, aiding in the identification of bioactive compounds and their applications in medicine and other industries.

InChI:InChI=1/C8H10N2/c1-7-8-3-2-5-10(8)6-4-9-7/h2-3,5H,4,6H2,1H3

Upstream product

• 1192-62-7 1-(2-furyl)-1-ethanone 
• 107-15-3 ethylenediamine 
• 7732-18-5 water 
• 73627-16-4 N-[2-(1H-pyrrol-1-yl)ethyl]acetamide 

Downstream Products

• 110254-46-1 1-Dicyanomethylen-2,3-diphenyl-8,9-dihydropyrrolo<1.2-a>-1H-pyridino<2'.1'-c>pyrazin 
• 110229-28-2 1-Dicyanomethylen-2,3-diphenyl-2,3,8,9-tetrahydropyrrolo<1.2-a>-1H-pyridino<2'.1'-c>pyrazin 
• 73627-24-4 1-Methyl-2-phenethyl-3,4-dihydro-pyrrolo[1,2-a]pyrazin-2-ium; bromide 
• 108201-01-0 10b-Methyl-2,3-diphenyl-1-oxo-1,5,6,10b-tetrahydrodipyrrolo<11.2-a;2'.1'-c>pyrazin 
• 108201-07-6 2-Ethoxy-10b-methyl-3,4-diphenyl-6,7-dihydro-2H,10bH-pyrrolo<1.2-a><1.3>thiazino<2.3-c>pyrazin 
• 64608-59-9 4-methylpyrrolo<1,2-a>pyrazine 
• 73627-18-6 1-Methyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 138747-14-5 2,4,6-Trimethyl-benzenesulfonate2-amino-1-methyl-3,4-dihydro-pyrrolo[1,2-a]pyrazin-2-ium; 
• 1260250-60-9 3-ethyl-6-methyl-5-tosyl-1,2,3,6-tetrahydropyrrolo[1,2-d][1,4]diazocine-9-carbaldehyde 
• 73627-23-3 1-Methyl-2-(2-phenylethyl)-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-19-7 1,2-Dimethyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 138747-33-8 C₂₂H₁₆N₃⁽¹⁺⁾*C₉H₁₁O₃S^(1-) 
• 108201-08-7 2-Methoxy-10b-methyl-3,4-diphenyl-6,7-dihydro-2H,10bH-pyrrolo<1.2-a><1.3>thiazino<2.3-c>pyrazin 
• 345892-00-4 2-(1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-ylidene)acetaldehyde 

Relevant academic research and scientific papers

Driving Recursive Dehydration by PIII/PV Catalysis: Annulation of Amines and Carboxylic Acids by Sequential C-N and C-C Bond Formation

A method for the annulation of amines and carboxylic acids to form pharmaceutically relevant azaheterocycles via organophosphorus PIII/PV redox catalysis is reported. The method employs a phosphetane catalyst together with a mild bromenium oxidant and terminal hydrosilane reductant to drive successive C-N and C-C bond-forming dehydration events via the serial action of a catalytic bromophosphonium intermediate. These results demonstrate the capacity of PIII/PV redox catalysis to enable iterative redox-neutral transformations in complement to the common reductive driving force of the PIII/PV couple.

Preparation method of N- phenyl-2-aminopyrimidine compound and its application

The invention relates to a new N- phenyl-2-aminopyrimidine compound and a medicine composition containing the compound; the N- phenyl-2-aminopyrimidine compound is applied to treat related disease or symptoms of epidermal growth factor receptor (EGFR), such as treat or improve abnormal cell proliferative disease like cancer.

CONVERSION OF PYRROLOPYRAZINIUM SALTS TO 8-AMINOINDOLIZINES

The recyclization of pyrrolopyrazinium salts under the influence of a base leads to 8-aminoindolizine derivatives and is a new method for the synthesis of indolizines, as well as the first example of the Kost-Sagitullin rearrangement in the pyrazin

AZACYCLOALKANES. XXIX. SYNTHESIS OF 1-SUBSTITUTED 3,4-DIHYDROPYRROLOPYRAZINES

The reaction of 2-acylfurans with ethylenediamine is a general method for the production of 1-substituted 3,4-dihydropyrrolopyrazines.