64621-35-8

Usage

Uses

Used in Organic Synthesis:
2,2’-(1,6-Hexanediyldioxy)bisbenzaldehyde is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure and reactivity make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Reactions:
HDDBA serves as a reagent in various chemical reactions, facilitating the formation of desired products and improving the efficiency of the reaction process. Its versatility as a reagent makes it suitable for use in a wide range of applications, including the synthesis of polymers, dyes, and other functional materials.
Used in Coordination Chemistry:
2,2’-(1,6-Hexanediyldioxy)bisbenzaldehyde is used as a ligand in coordination chemistry to form stable complexes with metal ions. These complexes exhibit unique properties and have potential applications in areas such as catalysis, sensing, and materials science.
Used in Catalytic Applications:
HDDBA, due to its ability to form stable complexes with metal ions, is used in catalytic applications to enhance the efficiency and selectivity of various chemical reactions. Its use as a catalyst or catalyst precursor can lead to improved reaction outcomes and reduced environmental impact.
Used in Pharmaceutical Development:
2,2’-(1,6-Hexanediyldioxy)bisbenzaldehyde is studied for its potential antimicrobial and antiviral properties, making it of interest in the development of new pharmaceuticals. Its unique chemical structure and reactivity may contribute to the discovery of novel therapeutic agents for the treatment of infectious diseases.
Used in Antimicrobial Applications:
HDDBA is used as an antimicrobial agent in various industries, including healthcare, food processing, and water treatment. Its ability to inhibit the growth of bacteria, fungi, and viruses makes it a valuable component in the development of disinfectants, sanitizers, and preservatives.
Used in Antiviral Applications:
2,2’-(1,6-Hexanediyldioxy)bisbenzaldehyde is explored for its potential antiviral properties, with applications in the development of antiviral drugs and treatments. Its ability to interfere with viral replication and infection processes may contribute to the prevention and control of viral diseases.

Upstream product

• 629-03-8 1 ,6-dibromohexane 
• 90-02-8 salicylaldehyde 
• 1346557-05-8 1,6-bis(2-iodophenoxy)hexane 
• 68-12-2 N,N-dimethyl-formamide 
• 629-11-8 1,6-hexanediol 
• 533-58-4 2-Iodophenol 
• 4672-50-8 1,6-bis(p-toluenesulfonyloxy)hexane 
• 2163-00-0 1,6-dichlorohexane 
• 4239-24-1 1,6-hexanediol dimethanesulfonate 

Downstream Products

• 214077-91-5 [hexane-1,6-diylbis(oxybenzene-2,1-diyl)]dimethanol 
• 1346557-06-9 1,6-bis(2-(2,2-dibromovinyl)phenoxy)hexane 
• 96172-85-9 1,6-bis(2-ethynylphenoxy)hexane 
• 1453500-87-2 1,6-bis(2-vinylphenoxy)hexane 
• 1629992-68-2 C₂₆H₃₀O₄ 
• 1036648-70-0 C₂₀H₂₄Cl₂O₂ 
• 1429339-61-6 1,6-bis(2-((allyloxy)methyl)phenoxy)hexane 

Relevant academic research and scientific papers

Synthesis, Spectroscopic, and Structural Studies of Extremely Short Chain Basket Handle Porphyrins and Their Zinc(II) Complexes

The synthesis of extremely short chain "basket handle" porphyrins is described.These molecules are derived from 5,10,15,20-tetraphenyl-21H,23H-porphine bearing alkoxy chains (handles) of 4-, 5-, and 6-carbon atoms covalently attached at the o-phenyl posit

Dinuclear platinum(II) complexes of imidazophenanthroline-based bridging ligands as potential anticancer agents: synthesis, characterization, and in vitro cytotoxicity studies

Abstract: The synthesis and characterization of the dinucleating ligands 1,2-bis(2-(1H-imidazo[4,5-f][1,10]phenanthrolin-2-yl)phenoxy)ethane (L1) and 1,2-bis(2-(1H-imidazo[4,5-f][1, 10]phenanthrolin-2-yl)phenoxy)hexane (L2) and their dinuclear complexes [

Prospective new amidinothiazoles as leukotriene B4 inhibitors

An efficient and one-step synthesis of the versatile, hitherto new derivatives resembling LY293111, a prospective potent antagonist of the leukotriene B4 (LTB4) receptor, were reported. The strategy was based on the synthesis of an amidinothiazole ring, c

Design, two-directional synthesis, DFT study of new pyrimido[5,4-d]pyrimidine-2,8-dione derivatives

A facile two-directional synthesis of new pyrimido[5,4-d]pyrimidine-2,8-dione was reported via an efficient reaction of premade bis-aldehydes and 1-(2-amino-1,2-dicyanovinyl)-3-phenylurea in the presence of triethylamine as the base and Cu (II) as catalys

Spacer length dependent architectural diversity in bis-dipyrrin copper(II) complexes

A series of copper(ii) complexes (1-9 and 3′) derived from bis-dipyrrin ligands (L1-L9 and L3′) with diverse spacer lengths [-(CH2)n-] have been described. Structural diversities in these complexes have been explicitly established by spectral and structural studies on these and a closely related nickel(ii) complex (3′′). All the ligands and complexes have been thoroughly characterized by spectroscopic studies (ESI-MS, IR, 1H, 13C NMR, UV/vis) and structures of 2, 3′, 3′′, 6, 8 and 9 were determined by X-ray single crystal analyses. It has been unambiguously established that ligands with n ≤ 6 gave heteroleptic binuclear (1-5), while those with n ≥ 7 yielded homoleptic mononuclear (6-9) bis-dipyrrinato complexes. Spectral and structural studies revealed distorted square planar (1-5) and distorted tetrahedral geometries (6-9) about the copper(ii) centre in these complexes which has further been evidenced by EPR and electrochemical studies. Structural differences based on the odd and even number of methylene spacers in these complexes have been supported by DFT studies. A line between the syn- and anti-conformations of the complexes has been drawn on the basis of a limiting spacer length.

Synthesis, structural characterization and extraction studies of 17-, 18-, 19- and 20-membered N2O2-donor macrocyclic Schiff bases

Two new macrocyclic Schiff bases m3 and m4 (m3?=?1,5-diaza-2,4:7,8:17,18-tribenzo-9,16-dioxa-cyclononadeca-1,5-dien; m4?=?1,5-diaza-2,4:7,8:18,19- tribenzo-9,17-dioxa-cycloeicosa-1,5-dien) were synthesized by reactions of the appropriate dialdehyde and di

One-pot synthesis of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols and evaluation of their antimicrobial activity

Abstract A new series of bis(4,5-diphenylimidazol-2-yl-phenyl)glycols were synthesized by reaction of bis(formylphenyl)glycols with benzil/benzoin and ammonium acetate in presence of iodine/acetic acid in ethanol. All newly synthesized compounds were char

Ring-closing metathesis reaction-based synthesis of new classes of polyether macrocyclic systems

Ring closing metathesis (RCM) reactions of suitable substrates having terminal olefins, which are assembled from various linkers and hydroxy benzaldehydes and syntheses of a wide range of 16-30 membered, new crown ether-type polyether, aza-polyether, bis aza-polyether macrocycles and dilactone moiety embedded polyether macrocycles (macrolides) are reported. After the ring-closure reaction, installation of different functional groups and functional group modification on the periphery of the synthesized polyether/crown ether macrocycles obtained in the RCM reactions are accomplished using the epoxidation, oxidation and catalytic hydrogenation-based synthetic transformations. Along this line, the syntheses of a variety of polyether macrocycles possessing epoxide or α-hydroxy ketone or 1,2-diol functionalities at the periphery have been shown. Furthermore, the synthesized α-hydroxy ketone functionality installed polyether macrocycles were subjected to the allylation and Reformatsky type reactions to obtain homoallyl alcohol moiety-based and lactone ring-appended polyether macrocycles.

Novel Bis(2-(5-((5-phenyl-1H-tetrazol-1-yl)methyl)-4H-1,2,4-triazol-3-yl)phenoxy)Alkanes: Synthesis and Characterization

In this study, 10 different substituted aromatic bis-benzaldehydes were synthesized by treating hydroxy benzaldehydes with various dihaloalkanes. Bis aldehydes 5a, 5b, 5c, 5d, 5e, 5f, 5g, 5h, 5i, 5j were treated with 2-(5-phenyl-1H-tetrazole-1-yl)acetohyd

Hexahelicenophanes

A reaction sequence was studied for the preparation of cyclophanes 12, which contain 2,7-bis(2-phenylethenyl)naphthalene chromophores and polymethylenedioxy chains of different length. The irradiation of 12 in the presence of I2 led then, by ox