64908-64-1

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-phenoxy-
• CAS NO: 64908-64-1
• Molecular Formula: C14H9NO3
• Molecular Weight: 239.23
• Mol File: 64908-64-1.mol
• Article Data: 33

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-phenoxy-(64908-64-1)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-phenoxy-(64908-64-1)

Safety Data

• Hazardous Substances Data: 64908-64-1(Hazardous Substances Data)

Upstream product

• 524-38-9 N-hydroxyphthalimide 
• 98-80-6 phenylboronic acid 
• 58109-40-3 diphenyliodonium hexafluorophosphate 
• 85-44-9 phthalic anhydride 

Downstream Products

• 6307-13-7 2-(2-hydroxyphenyl) isoindoline-1,3-dione 
• 106-48-9 4-chloro-phenol 
• 92-69-3 4-Phenylphenol 
• 90-43-7 2-Phenylphenol 
• 15171-63-8 N-phenoxy-1-benzyloxyformamide 
• 3487-90-9 n-butyl (E)-3-(o-hydroxyphenyl)acrylate 

Relevant articles and documents

Total Synthesis of (±)-Impatien A via Aza-Heck Cyclization

The first total synthesis of the natural product impatien A is described. This concise synthesis features an aza-Heck cyclization to construct the complex spirocyclic ring system and provides a rare example of the use of aza-Heck cyclizations in complex molecule synthesis. To enable this key cyclization of an electrophilic nitrogen atom with a tetrasubstituted alkene, we utilized high-throughput experimentation to identify a new ligand and ultimately deliver impatien A in seven steps from known compounds.

Synthesis of ortho-phenolic sulfilimines via an intermolecular sulfur atom transfer cascade reaction

To expand the toolbox for the synthesis of ortho-phenolic sulfilimines, sigmatropic rearrangements were introduced to the field of sulfilimine chemistry. Herein we report a N-H sulfenylation/[2,3]-sigmatropic rearrangement cascade reaction. This mild reaction enables commercially available thiols to serve as the sulfenylation reagent and generates water as the sole byproduct. Moreover, the reaction has a wide substrate scope and can be conducted on a gram scale with excellent reaction efficiency.

Dual Directing-Groups-Assisted Redox-Neutral Annulation and Ring Opening of N-Aryloxyacetamides with 1-Alkynylcyclobutanols via Rhodium(III)-Catalyzed C-H/C-C Activations

A cascade [3 + 2] annulation and ring opening of N-aryloxyacetamides with 1-alkynylcyclobutanols via Rh(III)-catalyzed redox-neutral C-H/C-C activations using internal oxidative O-NHAc and -OH as the dual directing groups has been achieved. This reaction provided an efficient and regioselective approach to benzofuran derivatives with good functional group compatibility and high yields.