649719-83-5

Basic information

• Product Name: Adenosine, N-benzoyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-2-propenyl-
• CAS NO: 649719-83-5
• Molecular Formula: C26H35N5O5Si
• Molecular Weight: 525.68
• Mol File: 649719-83-5.mol

Chemical Properties

• CAS DataBase Reference: Adenosine, N-benzoyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine, N-benzoyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-2-propenyl-(649719-83-5)
• EPA Substance Registry System: Adenosine, N-benzoyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-2-propenyl-(649719-83-5)

Safety Data

• Hazardous Substances Data: 649719-83-5(Hazardous Substances Data)

Upstream product

• 649719-82-4 N-{9-[3-allyloxy-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-tetrahydro-furan-2-yl]-9H-purin-6-yl}-N-benzoyl-benzamide 
• 98-88-4 benzoyl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 51008-81-2 N⁶,N⁶-dibenzoyladenosine 
• 649719-89-1 N-[9-(3-allyloxy-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-N-benzoyl-benzamide 
• 126775-28-8 N-[9-(3-allyloxy-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-9H-purin-6-yl]-N-benzoyl-benzamide 

Downstream Products

• 649719-87-9 N-{9-[3-(tert-butyl-dimethyl-silanyloxymethyl)-6-methyl-5,8-dioxo-1,3,3a,6,7,8,9,10,13,14a-decahydro-5H-2,4,14-trioxa-7-aza-cyclopentacyclotridecen-1-yl]-9H-purin-6-yl}-benzamide 
• 649719-86-8 (S)-2-Pent-4-enoylamino-propionic acid (2R,3R,4R,5R)-4-allyloxy-5-(6-benzoylamino-purin-9-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Synthesis of 2'-O,3'-O bicyclic adenosine analogues using ring closing metathesis

The synthesis of 2'-O,3'-O bicyclic adenosine derivatives is presented as the first examples of a new family of 13-membered ring bicyclic nucleoside analogues. Cyclisation was achieved through ring closing metathesis (RCM) on a diene intermediate using Grubbs' catalyst. The Z and E isomers were purified and characterised.