649759-93-3 Usage
Uses
Used in Drug Development:
Uridine, 4-O-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)-, 5'-(2-cyano-1-phenylethyl carbonate) 3'-(hydrogen butanedioate) is used as a potential candidate for drug development due to its unique structure and functional groups. Its enhanced stability and bioavailability make it a promising candidate for the treatment of various diseases.
Used in Research Applications:
In the field of research, Uridine, 4-O-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)-, 5'-(2-cyano-1-phenylethyl carbonate) 3'-(hydrogen butanedioate) can be used as a research tool to study the effects of its functional groups on biological systems. This can help in understanding the mechanisms of action and potential therapeutic applications of similar compounds.
Used in Pharmaceutical Industry:
Uridine, 4-O-[2-(4-nitrophenyl)ethyl]-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)-, 5'-(2-cyano-1-phenylethyl carbonate) 3'-(hydrogen butanedioate) is used as a key intermediate in the synthesis of novel pharmaceutical compounds. Its unique structure and functional groups can be exploited to develop new drugs with improved efficacy and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 649759-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,5 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 649759-93:
(8*6)+(7*4)+(6*9)+(5*7)+(4*5)+(3*9)+(2*9)+(1*3)=233
233 % 10 = 3
So 649759-93-3 is a valid CAS Registry Number.
649759-93-3Relevant academic research and scientific papers
Nucleotides. Part LXXIII: Oligoribonucleotide synthesis with the (2-cyano-1-phenylethoxy)carbonyl (2c1peoc) group for the 5′-hydroxy protection
Muench, Ursula,Pfleiderer, Wolfgang
, p. 2546 - 2565 (2007/10/03)
The (2-cyano-1-phenylethoxy)carbonyl (2c1peoc) group was developed as a new base-labile protecting group for the 5′-OH function in solid-phase synthesis of oligoribonucleotides via the phosphoramidite approach. The half-lives of its β-elimination process by 0.1M DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) were determined to be 7-14s by HPLC investigations. The 2′-OH function was protected with the acid-labile tetrahydro-4-methoxy-2H-pyran-4-yl (thmp) group, while the 2-(4-nitrophenyl)ethyl (npe) and 2-(4-nitrophenyl)ethoxycarbonyl (npeoc) groups were used for the protection of the base and phosphate moieties. The syntheses of the monomeric building blocks, both phosphoramidites and nucleoside-functionalized supports, as well as the build-up of oligoribonucleotides by means of this approach are described.
