64984-08-3

Basic information

• Product Name: 1-Iodo-4-(methylsulfonyl)benzene
• Synonyms: 1-Iodo-4-(methylsulfonyl)benzene
• CAS NO: 64984-08-3
• Molecular Formula: C₇H₇IO₂S
• Molecular Weight: 282.09875
• Mol File: 64984-08-3.mol
• Article Data: 19

Chemical Properties

• Melting Point: 116-118 °C
• Boiling Point: 365.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.840±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Iodo-4-(methylsulfonyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Iodo-4-(methylsulfonyl)benzene(64984-08-3)
• EPA Substance Registry System: 1-Iodo-4-(methylsulfonyl)benzene(64984-08-3)

Safety Data

• Hazardous Substances Data: 64984-08-3(Hazardous Substances Data)

Usage

General Description

1-Iodo-4-(methylsulfonyl)benzene is a chemical compound with the molecular formula C7H7IO2S. It is an organoiodine compound that contains a benzene ring with a molecular structure consisting of a methylsulfonyl group and an iodine atom attached to it. 1-Iodo-4-(methylsulfonyl)benzene is used as a reagent in organic synthesis and medicinal chemistry, particularly in the production of pharmaceuticals and agrochemicals. It is also used in the manufacturing of dyes, imaging agents, and other specialty chemicals. 1-Iodo-4-(methylsulfonyl)benzene is known for its ability to undergo various chemical reactions, including substitution, elimination, and addition reactions, making it a versatile and important compound in the field of organic chemistry.

Upstream product

• 5470-49-5 4-methanesulfonylphenylamine 
• 4052-30-6 4-methylsulfonylbenzoic acid 
• 98-61-3 p-Iodobenzenesulfonyl chloride 
• 62696-04-2 TBHP 
• 2751-27-1 4-iodobenzenesulfonyl hydrazide 
• 149104-88-1 4-methanesulphonylphenylboronic acid 
• 104-96-1 4-methylsulfanylaniline 
• 35371-03-0 4-iodothioanisole 

Downstream Products

• 64528-20-7 3-(4-Iodo-benzenesulfonyl)-2-oxo-propionic acid ethyl ester 
• 6462-34-6 4-(methylsulfonyl)-1,1′-biphenyl 
• 603143-27-7 (4,4,5,5-tetramethyl-2-[4-(methylsulfonyl)phenyl])-1,3,2-dioxaborolane 
• 83642-28-8 1-bromo-4-(4-(methylsulfonyl)phenoxy)benzene 
• 105135-96-4 3-(4-(methylsulfonyl)phenyl)prop-2-yn-1-ol 

Relevant articles and documents

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

Method for catalyzing deaminized boric acid esterification or halogenation of arylamine

The invention belongs to the technical field of organic synthesis and in particular discloses a method for catalyzing deaminized boric acid esterification or halogenation of arylamine. The method comprises the following steps: putting arylamine and a nitroso type compound into a mixed solvent, and performing a reaction at 0-5 DEG; and further adding a raw material capable of providing a functionalization group A and a catalysis amount of a reaction accelerator, and performing deamination functionalization reaction under light radiation at 10-50 DEG C, so as to obtain a product that an amino site of the arylamine is modified by the functionalization group A. Due to synergetic control on substrates, reaction solvents, material mixing modes, temperatures, reaction accelerators and addition amounts, boric acid esterification or halogenation of arylamine, particularly electron donating substituted arylamine which is hard to treat effectively in technical schemes of the industry, can be achieved.

DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE

Provided herein are a dihydropyrimidine compound and a pharmaceutical application thereof, especially the application used for treating and preventing HBV diseases. Specifically, provided herein is a compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof, wherein the variables of the formulas are as defined in the specification. Also provided herein is use of the compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof as a medicine, especially for treating and preventing HBV diseases.