65007-55-8

Upstream product

• 5333-86-8 ethyl benzimidate hydrochloride 
• 100-16-3 4-nitrophenylhydrazone 
• 77721-75-6 (α-nitro-benzylidene)-(4-nitro-phenyl)-hydrazine 
• 7664-41-7 ammonia 
• 861568-85-6 N-(4-nitro-phenyl)-N-nitroso-benzamidrazone 
• 7732-18-5 water 
• 124051-65-6 2-(4-nitrophenyl)-3,5-diphenyl-2H-tetrazolium chloride 
• 57-14-7 N,N-Dimethylhydrazine 
• 100-47-0 benzonitrile 

Downstream Products

• 115591-25-8 5-ethyl-1-(4-nitrophenyl)-3-phenyl-1,2,4-triazole 
• 115591-24-7 5-methyl-1-(4-nitrophenyl)-3-phenyl-1H-1,2,4-triazole 
• 861568-85-6 N-(4-nitro-phenyl)-N-nitroso-benzamidrazone 

Relevant academic research and scientific papers

Chromogenic Reaction of 1,1-Dimethylhydrazine with Aryltetrazolium Salts

The reactions of 1,1-dimethylhydrazine with 2,3,5-triphenyl-2Н-tetrazolium and 2,5-diphenyl-3-(4-nitrophenyl)-2Н-tetrazolium chlorides in a solution and on a cellulose carrier have been studied by means of spectrophotometry and chromato–mass spectrometry to develop new chromogenic indicators for detection of 1,1-dimethylhydrazine. 1,3,5-Triphenylformazan and 1,3-diphenyl-5-(4-nitrophenyl)formazan are formed in these reactions, respectively; deep red shifts have been observed. Other products of these reactions result from oligomerization and addition of short-living 1,1-dimethylhydrazyl and tetrazolium radicals.

Formation of 1,2,4-Triazoles by Cation Radical Induced Oxidative Addition of Arylhydrazones of Benzaldehyde and Butyraldehyde to Nitriles

1,3,5-Trisubstituted 1,2,4-triazoles have been made in excellent yields by oxidative cycloaddition of arylhydrazones of benzaldehyde and butyraldehyde to aceto-, propio-, and acrylonitrile.Oxidation was achieved with the cation radicals thianthrenyl perchlorate (Th(radical)+ClO4-) and tris(2,4-dibromophenyl)aminium hexachloroantimonate (Ar3N(radical)+SbCl6-).The triazoles thus had a phenyl, p-nitrophenyl, or 2,4-dinitrophenyl group in the 1-position, either a phenyl or propyl group in the 3-position, and a methyl, ethyl, or vinyl group in the 5-position.The formation of 5-vinyltriazoles was confirmed by their hydrogenation to 5-ethyltriazoles, which were obtained also by cycloadditions to propionitrile.New triazoles (eight) were also synthesized by a known alternative route, but in lower yields.The fact that 5-vinyltriazoles were formed instead of 5-cyano-2-pyrazolines shows that cation radical induced cycloadditions do not go through the nitrilimines.Cycloadditions with N-phenylbenzohydrazonoyl chloride and acrylonitrile in the presence of aluminum chloride and of triethylamine were carried out for comparison with the corresponding cation radical reaction.