65084-17-5

Upstream product

• 62993-44-6 1-[(1S)-1-phenylethyl]pyrrolidine-2,5-dione 
• 618-36-0 rac-methylbenzylamine 
• 86841-96-5 1-(1-phenylethyl)-2,5-pyrrolidinedione 
• 60756-87-8 N-(1-phenylethyl)-succinamic acid 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 1285559-98-9 5-(1H-indol-3-yl)-1-(1-phenylethyl)pyrrolidin-2-one 
• 1285560-05-5 5-(2-methyl-1H-indol-3-yl)-1-(1-phenylethyl)pyrrolidin-2-one 
• 1285560-09-9 5-(2-p-tolyl-1H-indol-3-yl)-1-(1-phenylethyl)pyrrolidin-2-one 
• 126017-68-3 (5S)-(-)-1-<(1S)-1-Phenylethyl>-5-propyl-2-pyrrolidinone 
• 126017-66-1 (5R)-(-)-1-<(1S)-1-Phenylethyl>-5-propyl-2-pyrrolidinone 
• 129708-94-7 (S)-2-(4,4-Dimethoxy-butyl)-1-(1-phenyl-ethyl)-pyrrolidine 
• 129708-94-7 (2S)-(-)-2-(4,4-dimethoxybutyl)-1-((1S)-1-phenylethyl)-pyrrolidine 
• 129708-92-5 (2S)-(-)-2-(4-oxobut-1-yl)-1-((1S)-1-phenylethyl)-pyrrolidine 
• 129708-90-3 (2S)-(-)-1-((1S)-1-phenylethyl)-2-(1-prop-2-enyl)-pyrrolidine 
• 134457-83-3 5-sec-Butyl-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-one 
• 126017-85-4 N-<(S)-1'-Phenylethyl>-5-prop-2''-enylpyrrolidin-2-one 
• 134527-57-4 (R)-5-((R)-1-Methyl-allyl)-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-one 
• 134527-56-3 (R)-5-((S)-1-Methyl-allyl)-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-one 
• 134457-69-5 (S)-5-((R)-1-Methyl-allyl)-1-((S)-1-phenyl-ethyl)-pyrrolidin-2-one 

Relevant academic research and scientific papers

Regioselective synthesis of 1-alkyl-5-(indol-3-yl- and -2-yl)pyrrolidin-2- ones from available reagents

The reaction under mild conditions of 1-alkyl-5-hydroxypyrrolidin-2-ones with different indoles having a free 3 position leads exclusively to 1-alkyl-5-(indol-3-yl)pyrrolidin-2-ones but if position 3 is occupied to 1-alkyl-5-(indol-2-yl)pyrrolidin-2-ones.

Stereoselective Nucleophilic Additions to the Carbon-Nitrogen Double Bond. 3. Chiral Acyliminium Ions

(S)-(-)-α-Phenethylamine (3), (S)-(-)-1-(2-chlorophenyl)ethylamine (4), (S)-(-)-1-(2,6-dichlorophenyl)ethylamine (5), and (S)-(-)-1-(2,3,4,5,6-pentachlorophenyl)ethylamine (6) have been incorporated into acyliminium ions of structural type 1 and 2.Five-me