65128-67-8

Usage

Uses

Used in Pharmaceutical Industry:
2-(Methylthio)thiazolo[4,5-c]pyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its potential therapeutic properties. It is valued for its antimicrobial, antifungal, and anti-inflammatory effects, which contribute to the development of new drugs and treatments targeting a range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(Methylthio)thiazolo[4,5-c]pyridine serves as an intermediate in the production of compounds with pesticidal properties. Its unique chemical structure allows for the creation of agrochemicals that can combat various pests and diseases in agriculture, thereby enhancing crop protection and yield.
Ongoing Research:
MTTP is currently the subject of ongoing research aimed at exploring its potential uses in medicinal and agricultural applications further. The exploration of its unique properties and structure is expected to lead to the discovery of new applications and advancements in drug development and crop protection strategies.

InChI:InChI=1/C7H6N2S2/c1-10-7-9-5-4-8-3-2-6(5)11-7/h2-4H,1H3

Upstream product

• 57135-09-8 1H,2H-[1,3]thiazolo[5,4-b]pyridine-2-thione 
• 74-88-4 methyl iodide 
• 20511-15-3 3-amino-4-chloropyridine 
• 65128-66-7 2-mercapto-pyrido[3,4-d][1,3]thiazole 
• 13091-23-1 4-chloro-3-nitropyridine 
• 65128-66-7 thiazolo[4,5-c]pyridine-2(3H)-thione 

Relevant academic research and scientific papers

General Entry into o-,o′-Heteroatom-Linked N-(Hetero)aryl-Imidazole Motifs by Gold-Catalysed Formal [3+2]-Dipolar Cycloaddition

A general redox-neutral approach into the o-,o′-heteroatom-linked N-(hetero)aryl-imidazole family of heteroaromatics has been developed. New types of heteroatom substituted carbimidoyl nitrenoids are efficiently realised from robust, bench-stable N-(heteroaryl)-pyridinium-N-aminides by formal gold-catalysed [3+2]-dipolar cycloadditions across ynamides. Broad structural variety and functional group tolerance allows rapid access into diverse functionalised scaffolds, as exemplified by the preparation of 8 different heteroaromatic cores. (Figure presented.).

Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists

In search for a new lead of non-imidazole histamine H3-receptor antagonists, a series of 1[(2-thiazolopyridine)-4-n-propyl]piperazines, the analogous 1-[(2-oxazolopyridine)-4-npropyl]piperazines, 1-[(2-benzothiazole)-4- n-propyl]piperazine and 1-[(2-benzooxazole)4-n-propyl]piperazine were prepared and in vitro tested as H3-receptor antagonists (the electrically evoked contraction of the guinea-pig jejunum). It appeared that by comparison of homologous pairs the thiazolo derivatives have slightly higher activity than their oxazolo analogues. The most potent compound of these series is the 1-(2-thiazolo[4,5-c]pyridine)-4-n-propylpiperazine (3c) with pA2 = 7.25 (its oxazole analogue (4g) showed pA2 = 6.9). The structure-activity relationships for compounds with various positions of the nitrogen in the benzene ring for the thiazoles compared with oxazoles are discussed.