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Z-Aib-Pro-Aib-Ala-OMe is a synthetic peptide composed of five amino acids: Z-Aib (N-benzyloxycarbonyl-α-aminoisobutyric acid), Pro (proline), Aib (α-aminoisobutyric acid), Aib (α-aminoisobutyric acid), and Ala-OMe (α-amino-n-methylacetate). This peptide is characterized by its unique structure, featuring two Aib residues, which are non-natural amino acids that promote the formation of β-turns in peptide structures. The presence of Pro and the N-methyl group in Ala-OMe further contribute to the peptide's conformational properties. Z-Aib-Pro-Aib-Aib-Ala-OMe is often used in research to study peptide folding, stability, and interactions, as well as in the development of new drugs and bioactive compounds.

65148-45-0

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65148-45-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 65148-45-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,1,4 and 8 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 65148-45:
(7*6)+(6*5)+(5*1)+(4*4)+(3*8)+(2*4)+(1*5)=130
130 % 10 = 0
So 65148-45-0 is a valid CAS Registry Number.

65148-45-0Relevant academic research and scientific papers

RACEMIZATION AT PROLINE RESIDUES DURING PEPTIDE BOND FORMATION A STUDY OF DIASTEREOMERIC MIXTURES OF SYNTHETIC ALAMETHICIN FRAGMENTS BY 270 MHz 1H NMR

Nagaraj, R.,Balaram, P.

, p. 2001 - 2006 (1981)

The stepwise synthesis of amino terminal pentapeptide of alamethicin, Z-Aib-Pro-Aib-Ala-Aib-OMe, by the dicyclohexylcarbodiimide mediated couplings leads to extensive racemization at the Ala and Pro residues.Racemization is largely suppressed by the use o

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