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2-Bromo-5-fluoro-3-nitropyridine, with the molecular formula C5H2BrFN2O2 and CAS number 884495-29-4, is a chemical compound that features a pyridine ring with a bromo group (Br), a fluoro group (F), and a nitro group (NO2) attached to it. This six-membered aromatic heterocycle is known for its unique chemical characteristics, making it a valuable building block in organic synthesis for creating more complex molecules. Due to its potential for hazardous reactions, it is essential to handle 2-BROMO-5-FLUORO-3-NITROPYRIDINE with care and follow proper safety guidelines during storage and use.

652160-72-0

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652160-72-0 Usage

Uses

Used in Organic Synthesis:
2-Bromo-5-fluoro-3-nitropyridine is used as a building block in the field of organic synthesis for the creation of more complex molecules. Its distinct functional groups allow for various chemical reactions, making it a versatile compound for constructing a wide range of chemical structures.
Used in Chemical Research:
In the realm of chemical research, 2-Bromo-5-fluoro-3-nitropyridine is employed as a subject of study to understand the properties and reactivity of compounds with multiple functional groups. This knowledge can be applied to develop new synthetic methods and improve existing ones, ultimately contributing to the advancement of chemistry.
Used in Pharmaceutical Development:
2-Bromo-5-fluoro-3-nitropyridine is used as a starting material in the development of new pharmaceutical compounds. Its unique structure and reactivity can be harnessed to create potential drug candidates with novel therapeutic properties, offering new treatment options for various medical conditions.
Used in Material Science:
In material science, 2-Bromo-5-fluoro-3-nitropyridine is utilized in the synthesis of new materials with specific properties, such as improved stability or enhanced reactivity. These materials can be used in various applications, including coatings, adhesives, and other industrial products.

Check Digit Verification of cas no

The CAS Registry Mumber 652160-72-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,2,1,6 and 0 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 652160-72:
(8*6)+(7*5)+(6*2)+(5*1)+(4*6)+(3*0)+(2*7)+(1*2)=140
140 % 10 = 0
So 652160-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H2BrFN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H

652160-72-0 Well-known Company Product Price

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  • Alfa Aesar

  • (H64208)  2-Bromo-5-fluoro-3-nitropyridine, 95%   

  • 652160-72-0

  • 250mg

  • 980.0CNY

  • Detail
  • Alfa Aesar

  • (H64208)  2-Bromo-5-fluoro-3-nitropyridine, 95%   

  • 652160-72-0

  • 1g

  • 2940.0CNY

  • Detail

652160-72-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-5-fluoro-3-nitropyridine

1.2 Other means of identification

Product number -
Other names 2-Bromo-5-fluoro-3-nitro-pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:652160-72-0 SDS

652160-72-0Relevant articles and documents

Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4- fluoro-7-[1,2,3]triazol-1-yl-1H-

Regueiro-Ren, Alicia,Xue, Qiufen M.,Swidorski, Jacob J.,Gong, Yi-Fei,Mathew, Marina,Parker, Dawn D.,Yang, Zheng,Eggers, Betsy,D'Arienzo, Celia,Sun, Yongnian,Malinowski, Jacek,Gao, Qi,Wu, Dedong,Langley, David R.,Colonno, Richard J.,Chien, Caly,Grasela, Dennis M.,Zheng, Ming,Lin, Pin-Fang,Meanwell, Nicholas A.,Kadow, John F.

, p. 1656 - 1669 (2013/04/23)

A series of highly potent HIV-1 attachment inhibitors with 4-fluoro-6-azaindole core heterocycles that target the viral envelope protein gp120 has been prepared. Substitution in the 7-position of the azaindole core with amides (12a,b), C-linked heterocycl

Aminium salts of 1,2,3-triazoles as prodrugs of drugs including antiviral agents

-

Page/Page column 11; 14, (2008/06/13)

This disclosure provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the disclosure is concerned with new aminium salts of 1,2,3-triazoles which can be used as prodrugs to improve

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

-

, (2008/06/13)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiv

Prodrugs of piperazine and substituted piperidine antiviral agents

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Page/Page column 31; 32, (2010/02/14)

This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.

Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives

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Page 212, (2008/06/13)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with azaindoleoxoacetyl piperazine derivatives. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS.

Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives

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Page/Page column 37, (2010/02/05)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with sulfonylureido piperazine derivatives of Formula I. These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. 1wherein: Z is 2Q is selected from the group consisting of: 3—W— is 4—represents a carbon-carbon bond or does not exist; and A is NR13R14.

INDOLE, AZAINDOLE AND RELATED HETEROCYCLIC UREIDO AND THIOUREIDO PIPERAZINE DERIVATIVES

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Page 79, (2010/02/06)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with ureido and thioureido piperazine derivatives of Formula (I). These compounds possess unique antiviral activity, whether used alone or in combination with other antivirals, antiinfectives, immunomodulators or HIV entry inhibitors. More particularly, the present invention relates to the treatment of HIV and AIDS. The compounds of Formula (I) are Formula (I) wherein:Y is O or S;Z is Formula (II); Q is selected from the group consisting of Formula (A) and Formula (B); m is 2;A is NRR; and-W- is Formula (C).

Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides

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Page/Page column 126, (2010/02/06)

This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with new piperidine 4-alkenyl derivatives that possess unique antiviral activity. More particularly, the present invention relates to compounds useful for the treatment of HIV and AIDS. The compounds of the invention for the general Formula I: wherein: Z is Q is selected from the group consisting of: —W— is

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