6526-78-9

Basic information

• Product Name: 1-AMINO-1-METHYLCYCLOHEXANE
• Synonyms: 1-AMINO-1-METHYLCYCLOHEXANE;(1-methylcyclohexyl)amine(SALTDATA: HCl);1-MethylcyclohexanaMine;1-Amino-1-Methylcyclohexane(WX604567)
• CAS NO: 6526-78-9
• Molecular Formula: C₇H₁₅N
• Molecular Weight: 113.2007
• Mol File: 6526-78-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 39-40℃
• Boiling Point: 143-145℃
• Flash Point: 27.5±9.7℃
• Appearance: /
• Density: 0.854±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.4547 (13℃)
• PKA: 10.95±0.70(Predicted)
• CAS DataBase Reference: 1-AMINO-1-METHYLCYCLOHEXANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINO-1-METHYLCYCLOHEXANE(6526-78-9)
• EPA Substance Registry System: 1-AMINO-1-METHYLCYCLOHEXANE(6526-78-9)

Safety Data

• Hazardous Substances Data: 6526-78-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 95, p. 4083, 1973 DOI: 10.1021/ja00793a062

Upstream product

• 1123-25-7 1-methyl-1-cyclohexanecarboxylic acid 
• 590-67-0 1-Methylcyclohexanol 
• 151-50-8 potassium cyanide 
• 82166-21-0 methyl cyclohexane 
• 142-96-1 dibutyl ether 
• 7664-93-9 sulfuric acid 
• 7443-52-9 (+/-)-trans-2-methylcyclohexanol 
• 7443-55-2 rac-trans-3-methylcyclohexanol 
• 5454-79-5 cis-3-methylcyclohexanol 
• 591-49-1 1-methylcyclohex-1-ene 
• 22530-83-2 1-azido-1-methylcyclohexane 
• 502-41-0 cycloheptanol 
• 52829-98-8 1-cyclopentylethan-1-ol 
• 22086-20-0 N-(1-Methylcyclohexyl)-carbaminsaeure-amylester 

Downstream Products

• 59368-15-9 1-Methyl-1-nitrocyclohexane 
• 3276-34-4 1-Nitroso-1-methyl-cyclohexan 
• 42066-84-2 N-<1-Methyl-cyclohexyl>-hydroxylamin 
• 6044-86-6 1,3,5,7-tetra(1-methylcyclohexyl)-2,4,6,8-tetrachloro-cyclo-1,3,5,7-tetraaza-2,4,6,8-tetraborane 
• 98956-57-1 dimethyl-(1-methyl-cyclohexyl)-amine oxide 
• 42066-92-2 N-(1-Methylcyclohexyl)-N'-phenyl-N-hydroxyharnstoff 
• 42067-02-7 N-(1-Methylcyclohexyl)-O-(phenylcarbamoyl)-hydroxylamin 
• 13909-08-5 C₁₀H₁₈ClN₃O₂ 
• 4194-13-2 morpholine-4-sulfonic acid (1-methyl-cyclohexylcarbamoyl)-amide 
• 109436-34-2 1,1'-Dimethyl-azoxycyclohexan 
• 345252-04-2 benzyl-(1-methyl-cyclohexyl)-amine 
• 114035-89-1 methyl-(1-methyl-cyclohexyl)-amine 
• 152643-40-8 N-(1-methylcyclohexyl)iodoacetamide 

Relevant articles and documents

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METHODS OF TREATING CNS DISORDERS

The present invention relates to methods of treating various CNS disorders, e.g., mania, bipolar disorder and schizophrenia, by administering NMDA receptor antagonists, alone or in combination with dopamine receptor antagonists.

Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors

The invention relates to a novel drug combination therapy useful in the treatment of dementia comprising administering an 1-aminocyclohexane derivative such as memantine or neramexane and an acetylcholinesterase inhibitor (AChEI) such as galantamine, tacrine, donepezil, or rivastigmine.