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Anthranilic acid-(2,2,2-trifluoro-ethyl ester) is a chemical compound with the molecular formula C9H8F3NO3. It is an ester derivative of anthranilic acid, where the hydroxyl group is replaced by a trifluoroethyl ester group. anthranilic acid-(2,2,2-trifluoro-ethyl ester) is characterized by its fluorinated side chain, which can influence its reactivity and physical properties. It is often used in the synthesis of various pharmaceuticals and agrochemicals due to its potential to modify the activity and selectivity of the parent molecule. The trifluoroethyl ester group can be hydrolyzed under certain conditions to regenerate the parent anthranilic acid, making it a useful protecting group in organic synthesis.

653-96-3

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653-96-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 653-96-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 653-96:
(5*6)+(4*5)+(3*3)+(2*9)+(1*6)=83
83 % 10 = 3
So 653-96-3 is a valid CAS Registry Number.

653-96-3Relevant academic research and scientific papers

Hofmann-type rearrangement of imides by in situ generation of imide-hypervalent iodines(III) from iodoarenes

Moriyama, Katsuhiko,Ishida, Kazuma,Togo, Hideo

, p. 946 - 949 (2012/05/05)

The Hofmann-type rearrangement of aromatic and aliphatic imides using a hypervalent iodine(III) reagent generated in situ from PhI, m-CPBA, and TsOH·H2O proceeded in the presence of a base in alcohol to provide anthranilic acid derivatives and amino acid derivatives in high yields, respectively. This reaction proceeds through a tandem reaction via alcoholysis followed by a Hofmann rearrangement promoted by the formation of an imide-λ3-iodane intermediate.

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