65341-82-4

Basic information

• Product Name: Benzenemethanol, 2-bromo-5-methoxy-4-(phenylmethoxy)-
• CAS NO: 65341-82-4
• Molecular Formula: C15H15BrO3
• Molecular Weight: 323.186
• Mol File: 65341-82-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-bromo-5-methoxy-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-bromo-5-methoxy-4-(phenylmethoxy)-(65341-82-4)
• EPA Substance Registry System: Benzenemethanol, 2-bromo-5-methoxy-4-(phenylmethoxy)-(65341-82-4)

Safety Data

• Hazardous Substances Data: 65341-82-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 60632-40-8 6-bromovanillin 
• 52783-83-2 4-acetoxy-2-bromo-5-methoxybenzaldehyde 
• 881-68-5 vanillin acetate 
• 121-33-5 vanillin 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 33693-48-0 4-benzyloxy-3-methoxybenzyl alcohol 
• 40705-22-4 4-benzyloxy-6-bromo-3-methoxybenzaldehyde 

Downstream Products

• 222622-96-0 5-(benzyloxy)-1-bromo-2-(bromomethyl)-4-methoxybenzene 
• 139016-00-5 6-(Benzyloxy)-5-methoxyisobenzofuran-1(3H)-one 
• 331248-82-9 4-{4-[(E)-2-(4-Benzyloxy-2-bromo-5-methoxy-phenyl)-vinyl]-phenoxy}-6-[(E)-2-(5-benzyloxy-2-bromo-phenyl)-vinyl]-2,2-diphenyl-benzo[1,3]dioxole 
• 331248-79-4 (E)-1-[[4-(5-dimethylphosphonomethyl-2,3-diphenylmethylenedioxy)phenoxy]phenyl]-2-[2-bromo-4-benzyloxy-5-methoxyphenyl]ethene 
• 331248-77-2 (E)-1-[[4-(5-methoxycarbonyl-2,3-diphenylmethylenedioxy)phenoxy]phenyl]-2-[2-bromo-4-benzyloxy-5-methoxyphenyl]ethene 
• 331248-70-5 dimethyl 2-bromo-4-benzyloxy-5-methoxybenzylphosphonate 
• 40705-22-4 4-benzyloxy-6-bromo-3-methoxybenzaldehyde 
• 139015-94-4 1-<<4-(Benzyloxy)-2-bromo-5-methoxyphenyl>methoxy>-N,N-dimethylmethanamide 

Relevant articles and documents

cGAS ANTAGONIST COMPOUNDS

Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.

Sequential one-pot method for oxy-Michael addition, Heck coupling, and degradation followed by condensation: Facile synthesis of 2-benzoxepin-3(1H)- ones Dedicated to the memory of my teacher Professor P.V. Subba Rao, Department of Chemistry, Andhra University, Visakhapatnam

A sequential one-pot intermolecular oxy-Michael addition, intermolecular Heck coupling, and intramolecular degradation (retro-oxy-Michael addition) followed by condensation method has been developed for the synthesis of interesting 2-benzoxepin-3(1H)-ones. Significantly, the 2-benzoxepin-3(1H)-ones form the core quantum of biologically vital natural products. The initial oxy-Michael addition and Heck coupling steps involve a straight forward construction of C-O and C-C bonds, whereas, the final condensation step follows a novel mechanistic path via intramolecular degradation, double bond isomerization, and intramolecular condensation. Notably, a remarkable solvent effect has been observed in-order to promote the final intramolecular condensation.

Total syntheses of plagiochins A and D, macrocyclic bis(bibenzyls), by Pd(0) catalyzed intramolecular Stille-Kelly reaction

Total syntheses of plagiochins A (1) and D (4), the former of which exhibits a significant neurotrophic activity, have been accomplished. The key 16-membered ring closure in 4 has been achieved directly from the dibromoperrottetin derivative (7) by Pd(0)