654067-58-0

Basic information

• Product Name: Carbamic acid, [2,2-dimethyl-5-[4-(4-octylphenyl)-1H-imidazol-2-yl]-1,3-dioxan-5-yl]-, 1,1-dimethylethyl ester
• CAS NO: 654067-58-0
• Molecular Formula: C28H43N3O4
• Molecular Weight: 485.667
• Mol File: 654067-58-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2,2-dimethyl-5-[4-(4-octylphenyl)-1H-imidazol-2-yl]-1,3-dioxan-5-yl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2,2-dimethyl-5-[4-(4-octylphenyl)-1H-imidazol-2-yl]-1,3-dioxan-5-yl]-, 1,1-dimethylethyl ester(654067-58-0)
• EPA Substance Registry System: Carbamic acid, [2,2-dimethyl-5-[4-(4-octylphenyl)-1H-imidazol-2-yl]-1,3-dioxan-5-yl]-, 1,1-dimethylethyl ester(654067-58-0)

Safety Data

• Hazardous Substances Data: 654067-58-0(Hazardous Substances Data)

Upstream product

• 31827-94-8 2-bromo-1-(4-iodophenyl)ethanone 
• 13329-40-3 4-Iodoacetophenone 
• 364631-72-1 tert-butyl N-[5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-5-yl]carbamate 
• 364631-73-2 tert-butyl 5-formyl-2,2-dimethyl-1,3-dioxan-5-ylcarbamate 
• 53104-32-8 (5-amino-2,2-dimethyl-1,3-dioxan-5-yl)methanol 
• 629-05-0 n-octyne 
• 863483-01-6 5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxane-5-carboxylic acid 2-(4-iodo-phenyl)-2-oxo-ethyl ester 
• 654067-57-9 {5-[5-(4-iodo-phenyl)-1H-imidazol-2-yl]-2,2-dimethyl-[1,3]dioxan-5-yl}-carbamic acid tert-butyl ester 
• 654067-56-8 5-((tertbutoxycarbonyl)amino)-2,2-dimethyl-1,3-dioxane-5-carboxylic acid 
• 863483-02-7 {2,2-dimethyl-5-[5-(4-oct-1-ynyl-phenyl)-1H-imidazol-2-yl]-[1,3]dioxan-5-yl}-carbamic acid tert-butyl ester 

Downstream Products

• 863483-03-8 {2-hydroxy-1-hydroxymethyl-1-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-ethyl}-carbamic acid tert-butyl ester 
• 863482-95-5 {2-(tert-butyl-dimethyl-silanyloxy)-1-hydroxymethyl-1-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-ethyl}-carbamic acid tert-butyl ester 
• 863482-96-6 {1-(tert-butyl-dimethyl-silanyloxymethyl)-2-(di-tert-butoxy-phosphoryloxy)-1-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-ethyl}-carbamic acid tert-butyl ester 
• 863482-98-8 {1-(tert-butyl-dimethyl-silanyloxymethyl)-2-(di-tert-butoxy-thiophosphoryloxy)-1-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-ethyl}-carbamic acid tert-butyl ester 

Relevant articles and documents

ORALLY AVAILABLE SPHINGOSINE 1-PHOSPHATE RECEPTOR AGONISTS AND ANTAGONISTS

The present invention relates to S1P analogs that have activity as S1Preceptor modulating agents and the use of such compounds to treat diseases associated with inappropriate S1P receptor activity. The compounds have the general structure (I) wherein R11 is C5-C18 alkyl or C5-C18 alkenyl; Q is selected from the group consisting of C3-C6 optionally substituted cycloalkyl, C3-C6 optionally substituted heterocyclic, C3-C6 optionally substituted aryl C3-C6 optionally substituted heteroaryl and; R2 is selected from the group consisting of H, C1-C4 alkyl, (C1-C4 alkyl)OH and (C1-C4 alkyl)NH2; R23 is H or C1-C4 alkyl, and R15 is a phosphonate ester or a phosphate ester or a pharmaceutically acceptable salt or tautomer thereof.