863483-01-6Relevant articles and documents
Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1- phosphate and FTY720: Discovery of potent S1P1 receptor agonists
Clemens, Jeremy J.,Davis, Michael D.,Lynch, Kevin R.,Macdonald, Timothy L.
, p. 3568 - 3572 (2007/10/03)
The novel immunosuppressant FTY720 has been demonstrated to elicit immunomodulating effects via interaction with the G-protein coupled receptor S1P1. FTY720 induced agonism at the S1P3 receptor, however, has been shown to result in m