65427-32-9Relevant academic research and scientific papers
Synthesis of α,γ-peptide hybrids by selective conversion of glutamic acid units
Saavedra, Carlos J.,Boto, Alicia,Hernández, Rosendo
supporting information; experimental part, p. 3542 - 3545 (2012/08/28)
The site-selective modification of small peptides at a glutamate residue allows the ready preparation of α,γ-hybrids. In this way, a single peptide can be transformed into a variety of hybrid derivatives. The process takes place under very mild conditions, and good global yields are obtained.
Application of an intramolecular dipolar cycloaddition to an asymmetric synthesis of the fully oxygenated tricyclic core of the stemofoline alkaloids
Carra, Ryan J.,Epperson, Matthew T.,Gin, David Y.
, p. 3629 - 3641 (2008/09/20)
An intramolecular non-stabilized azomethine ylide dipolar cycloaddition was applied toward the first non-racemic synthesis of the fully oxygenated bridged pyrrolizidine core (45) of (+)-stemofoline (1) in 11 steps from a commercially available starting material.
