65427-66-9Relevant academic research and scientific papers
Base assisted substitution of α-amidoalkyl sulfones by nitromethane anion. A new entry to functionalized α-amino acids
Ballini, Roberto,Petrini, Marino
, p. 4449 - 4452 (2007/10/03)
The nitromethane anion reacts with α-amidoalkyl sulfones in THF affording the corresponding nitro derivatives that upon oxidation with alkaline potassium permanganate give the corresponding N-protected α-amino acids.
LES ORGANOCUPRATES DANS UNE NOUVELLE SYNTHESE D'AMINOACIDES ENANTIOMERIQUEMENT PURS
Bajgrowicz, J. A.,Hallaoui, A. El,Jacquier, R.,Pigiere, Ch.,Viallefont, Ph.
, p. 1833 - 1845 (2007/10/02)
A new general method of synthesis of optically pure α- amino esters was elaborated during studies on the reaction of organocuprates with tosyl and halogeno derivatives of L-serine and L-homoserine.
UTILISATION DES ORGANOCUPRATES A LA SYNTHESE D'AMINOACIDES
Bernardini, A.,Hallaoui, A. El,Jacquier, R.,Pigiere, Ch.,Viallefont, Ph.,Bajgrowicz, J.
, p. 3717 - 3720 (2007/10/02)
The reaction of the organocuprate R2CuLi with iodo, bromo or tosyl amino acids gives excellent yields of the substitution products without affecting the configuration of amino acids.
