6548-01-2Relevant academic research and scientific papers
Neat formic acid: An excellent N-formylating agent for carbazoles, 3- alkylindoles, diphenylamine and moderately weak nucleophilic anilines
Chakrabarty, Manas,Khasnobis, Shampa,Harigaya, Yoshihiro,Konda, Yaeko
, p. 187 - 200 (2007/10/03)
Neat formic acid alone efficiently N-formylates carbazoles, 3- alkylindoles, diphenylamine and even moderately weak nucleophilic anilines to furnish the corresponding N-formyl derivatives in 72-87% yields.
Efficient and simple methods for the introduction of the sulfonyl, acyl and alkyl protecting groups on the nitrogen of indole and its derivatives
Ottoni, Olivia,Cruz, Rosimeire,Alves, Robledo
, p. 13915 - 13928 (2007/10/03)
The benzenesulfonylation, acetylation, methylation and benzylation at the 1 position of indole and its derivatives with bases such as NaOH, KOH and NEt3 are presented. By using weaker bases than the traditional ones (BuLi, NaNH2, etc.), the process is simpler, more general and leads to the products in 80-100% yields. The chemoselectivity in compounds bearing more than one nitrogen is also demonstrated.
POLYMERISATION OF INDOLE. PART 2. A NEW INDOLE TRIMER
Ishii, Hisashi,Murakami, Keiko,Sakurada(nee Kawanabe), Eri,Hosoya, Katsuhiro,Murakami, Yasuoki
, p. 2377 - 2386 (2007/10/02)
Treatment of indole (1) with toluene-p-sulphonic acid in benzene provided the 2,3'-indole trimer (4), a positional isomer of the well known 3,3'-indole trimer (3).The structure of the new trimer (4) was established by comparitive studies with the trimers (3) and (4).
Reactions entre l'indole et les chlorures d'acides, en milieu basique: Synthese d'amides de l'ortho -2 ethyl, aniline
Bourgeois, Paul,Mesdouze, Jean,Philogene, Emile
, p. 1043 - 1046 (2007/10/02)
Acid chlorides react with indole in alkaline aqueous medium and yield amides of o-aniline which is in fact a trimer of indole.Their formation can be understood as follows: autocondensation of indole to give 2,3-diindole; acylatio
