65490-22-4

Upstream product

• 2179-79-5 phenyl selenocyanate 
• 1201-71-4 4-biphenyllithium 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 1666-13-3 diphenyl diselenide 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 2051-62-9 4'-biphenyl chloride 
• 5122-94-1 4-biphenylboronic acid 
• 92-52-4 biphenyl 
• 4346-64-9 selenoanisole 
• 25862-09-3 phenylmethyl selenoxide 
• 1591-31-7 4-iodo-biphenyl 
• 23974-72-3 sodium phenylselenide 
• 72041-43-1 dimethyl 2-(phenylselenenyl)propanedioate 
• 5173-02-4 phenyl trifluoromethylselenide 

Downstream Products

• 125688-54-2 biphenyl-4-yl-dichloro-phenyl-λ⁴-selane 
• 109566-35-0 biphenyl-4-yl-dibromo-phenyl-λ⁴-selane 

Relevant academic research and scientific papers

Forging C?S(Se) Bonds by Nickel-catalyzed Decarbonylation of Carboxylic Acid and Cleavage of Aryl Dichalcogenides

A nickel-catalyzed decarbonylation of carboxylic acids cross-coupling protocol has been developed for the straightforward C?S(Se) bond formation. This reaction is promoted by a commercially-available, user-friendly, inexpensive, air and moisture-stable nickel precatalyst. Various carboxylic acids and a wide range of aryl dichalcogenide substrates were tolerated in this process which afforded products in good to excellent yields. In addition, the present reaction can be conducted on gram scale in good yield.

Cu-Mediated arylselenylation of aryl halides with trifluoromethyl aryl selenonium ylides

An unprecedented arylselenylation of aryl halides with trifluoromethyl aryl selenonium ylides in the presence of copper is described. The reaction proceeded at 100-140 °C under ligand- and additive-free conditions for 3-20 h to form a variety of unsymmetrical diaryl selenides in good to high yields. Arylselenylation is easy to operate, has good functional group tolerance, and demonstrates the different reaction profiles of trifluoromethyl aryl selenonium ylides from the homologous trifluoromethyl aryl sulfonium ylides.

Selenolation of Aryl Iodides and Bromides Enabled by a Bench-Stable PdI Dimer

The use of an air- and moisture-stable dinuclear PdI complex as an efficient catalyst for the formation of C(sp2)?SeR bonds is here reported. The privileged reactivity of the PdI dimer allows for the direct use of selenolates as nucleophiles in the cross-coupling. Although previous methodologies suffer from catalyst poisoning through the formation of Pd-ate complexes, the mechanistically distinct dinuclear PdI catalyst circumvents this challenge. A wide variety of aryl bromides and iodides were efficiently coupled under relatively mild reaction conditions with broad functional group tolerance. Mechanistic and computational data are presented in support of direct PdI reactivity.

Composition for preventing or treating cancer comprising novel selenobenzene compound

The present invention relates to a composition for preventing or treating cancer comprising, as an active ingredient, a novel selenobenzene compound represented by chemical formula 1. The selenobenzene compound according to the present invention inhibits

METHOD OF PREPARING CORE-SHELL COPPER NANOPARTICLES IMMOBILIZED ON ACTIVATED CARBON AND METHOD OF PREPARING CHALCOGENIDE COMPOUND USING NANOPARTICLES AS CATALYST

Disclosed herein is a method of preparing a Cu/Cu2O core-shell copper nanoparticle catalyst having high catalytic activity from [Cu3(BTC)2] and NaBH4 via a simple chemical reduction method. Also disclosed is a method of preparing a chalcogenide compound by using the nanoparticle catalyst as a heterogeneous catalyst in a cross-coupling reaction between a chalcogenide precursor compound and a boron-containing compound. The disclosed cross-coupling reaction is performed via a simple process, and the disclosed nanoparticle catalyst is compatible with various substrates under mild reaction conditions and exhibits excellent recyclability without a reduction in catalytic activity.

Copper nanoparticles catalyzed Se(Te)-Se(Te) bond activation: A straightforward route towards unsymmetrical organochalcogenides from boronic acids

A highly porous copper metal-organic framework, [Cu3(BTC)2] (BTC=benzene-1,3,5-tricarboxylate) was synthesized and used as a precursor for the synthesis of copper nanoparticles (NPs) and characterized by several techniques, including XRD, SEM, TEM, EDX and BET measurements. The as-synthesized copper nanoparticles were immobilized onto activated charcoal (AC) by means of ultrasonication at room temperature without any pretreatment. The Cu NPs/AC was employed as a heterogeneous catalyst for the cross-coupling of diphenyl diselenide and boronic acids to form diphenyl selenides through Se-Se bond activation under ligand-, base-, and additive-free conditions. The copper NPs/AC, which combines the architecture of MOFs and the high surface area of charcoal, could be an efficient heterogeneous catalytic system that is compatible with a variety of substituents on diphenyl selenides. Its promising catalytic activity relative to that of other homogeneous systems and low catalyst loading for the synthesis of unsymmetrical diaryl selenides is an important application in the area of nanocatalysis. The Cu NPs/AC catalyst, which exhibits excellent catalytic activity and remarkable tolerance to a wide variety of substituents, led to Se sp3-, sp2-, and sp-carbon bond formation by using DMSO as a solvent and atmospheric air as oxidant. This approach can also be extended to the preparation of unsymmetrical organotelluride derivatives. Three-in-one catalyst: Copper nanoparticles on activated charcoal show excellent catalytic activity towards the synthesis of unsymmetrical chalcogenides, starting from boronic acids, in air under ligand-, base-, and additive-free conditions, and resulting in selenium sp3-, sp2-, and sp-carbon bond formation.

Copper-catalyzed C-Se coupling of diphenyl diselenide with arylboronic acids at room temperature

An efficient synthetic protocol for the Cu-catalyzed cross-coupling of diphenyl diselenide and arylboronic acid at room temperature was described. This catalytic system could tolerate a variety of arylboronic acids with only 3 mol % amount of CuSO4 as the catalyst and inexpensive 1,10-phen. H 2O as the ligand. Moreover, this catalytic system used environment-friendly EtOH as the solvent and catalytic amount of Na 2CO3 (20 mol %) as the base in the air.

Electrochemically induced srn1 substitution in acetonitrile. Synthesis of arenes substituted by phenylseleno- and phenyltelluro groups

In MeCN, the direct or mediated cathodic reduction of unactivated ArBr (Ar = 4-biphenyl, 2-fluorenyl, 9-anthryl) in the presence of an equivalent of PhE- (E = Se, Te) leads to ArEPh in interesting isolated yields (53-74 %) by SNR1 substitution. The electrochemical synthesis of 9-phenylchalcogenoanthracene proceeds in better yields in MeCN than in DMSO. The 4,4′-disubstituted biphenyl PhSeC6H4C6H4SePh was prepared in 46 % yield in MeCN whereas its synthesis by photostimulation in liquid ammonia failed.