65492-27-5Relevant academic research and scientific papers
Efficient 2-sulfolmethyl quinoline formation from 2-methylquinolines and sodium sulfinates under transition-metal free conditions
Xiao, Fuhong,Chen, Shuqing,Chen, Ya,Huang, Huawen,Deng, Guo-Jun
, p. 652 - 654 (2015)
An efficient procedure for 2-sulfolmethyl quinoline preparation from 2-methylquinolines and sodium sulfinates under transition-metal free conditions is described. Halogen functional groups were well tolerated to give the corresponding products in good to
Base-controlled divergent synthesis of vinyl sulfones from (benzylsulfonyl)benzenes and paraformaldehyde
Xiao, Fuhong,Hu, Yangling,Huang, Huawen,Xu, Fen,Deng, Guo-Jun
supporting information, p. 3527 - 3535 (2020/05/25)
A tuneable metal-free protocol for the selective preparation of a-substituted vinyl sulfone and (E)-vinyl sulfone derivatives has been described. In this process, stable paraformaldehyde was used as the carbon source. The base played an important role in the selectivity control of transformations. More than 50 products were synthesized with excellent chemoselectivity and broad functional group tolerance.
Synthesis method of sulfonyl-containing quinoline compound
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Paragraph 0038-0044, (2019/09/14)
The invention provides a synthesis method of a sulfonyl-containing quinoline compound, and belongs to the field of organic synthesis. According to the synthesis method, no metal catalysts need to be used, reaction can be completed only under the action of a visible-light-induced photocatalyst, a reaction system is simple, heating is not needed in the reaction, and the reaction yield is high. According to the technical scheme, the synthesis method of the sulfonyl-containing quinoline compound comprises the steps of adding a quinoline compound and a sulfonyl chloride compound into a reactor separately, and under the action of the photocatalyst and a solvent acetone, carrying out room-temperature reaction for 4-12 hours under a condition of white LED lamp illumination; and after the reactionis completed, conducting column chromatography separation to obtain the sulfonyl-containing quinoline compound. The provided synthesis method provides an optimal alternative solving scheme for efficiently synthesizing the sulfonyl-containing quinoline compound.
Sulfonylation of C(sp3)–H bond for synthesis of 2-sulfolmethyl azaarenes catalyzed by TBAI in water
Dong, Dao-Qing,Gao, Xing,Li, Li-Xia,Hao, Shuang-Hong,Wang, Zu-Li
, p. 7557 - 7567 (2018/09/20)
A tetrabutylammonium iodide (TBAI)-catalyzed method for synthesis of 2-sulfolmethyl quinolone has been developed. Using water as solvent, a wide range of 2-sulfolmethyl quinolones were obtained in high to excellent yield. In addition, water and TBAI could be reused for five times without significant decrease of the yield of the corresponding product.
Efficient new protocol to synthesize aromatic and heteroaromatic dithioesters
Abrunhosa, Isabelle,Gulea, Mihaela,Masson, Serge
, p. 928 - 934 (2007/10/03)
A very efficient, high yielding procedure to synthesize substituted aromatic and heteroaromatic dithioesters is described. It involves the reaction between (phenylsulfonyl)methyl (hetero)aromatic derivatives and elemental sulfur in basic medium, followed by alkylation.
