655230-45-8

Usage

General Description

Benzenemethanol, 2-azido-5-bromo- is a chemical compound with the molecular formula C7H6BrN3O. It is an azide compound with a benzene ring and a bromine atom attached to the benzene ring. Benzenemethanol, 2-azido-5-bromo- is commonly used in the synthesis of pharmaceuticals, agrochemicals, and organic materials. It is also used in the research and development of new chemical compounds and materials. Benzenemethanol, 2-azido-5-bromo- is known for its potential uses in various chemical reactions and its role in the development of new products in the pharmaceutical and chemical industries.

Upstream product

• 20712-12-3 (2-amino-5-bromophenyl)methanol 
• 1001621-59-5 2-azido-5-bromobenzaldehyde 
• 93777-26-5 5-bromo-2-fluorobenzaldehyde 
• 5344-90-1 2-Aminobenzyl alcohol 
• 20615-76-3 2-azidobenzyl alcohol 

Downstream Products

• 655229-87-1 2-azido-5-bromobenzyl bromide 
• 655229-97-3 dithiocarbonic acid O-ethyl ester S-(2-azido-5-bromobenzyl) ester 
• 566942-93-6 dithiocarbonic acid S-(5-bromo-2-diphenylvinylideneamino-benzyl) ester O-ethyl ester 
• 655230-14-1 dithiocarbonic acid O-ethyl ester S-(5-bromo-2-triphenylphosphoranylideneamino)benzyl ester 
• 1245786-13-3 2-azido-5-bromobenzyl methanesulfonate 
• 1001621-59-5 2-azido-5-bromobenzaldehyde 

Relevant academic research and scientific papers

FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF

Provided herein are substituted fused quadracyclic compounds useful as inhibitors of MK2. The invention further provides pharmaceutical compositions of the compounds of the invention. The invention also provides medical uses of substituted fused quadracyclic compounds.

A simple route to polysubstituted indoles exploiting azide induced furan ring opening

A straightforward, efficient indole synthesis based on thermolysis of 2-(2-azidobenzyl)furans with attack of the formed nitrene moiety onto the ipso position of furan ring has been developed. The cyclization is accompanied by furan ring opening and affords indoles with a 2-acylvinyl substituent suitable for further modifications.

Design, synthesis, and in vitro pharmacology of new radiolabeled γ-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity γ-hydroxybutyric acid binding sites

γ-Hydroxybutyric acid (GHB) is a psychotropic compound endogenous to the brain. Despite its potential physiological significance, the complete molecular mechanisms of action remain unexplained. To facilitate the isolation and identification of the high-affinity GHB binding site, we herein report the design and synthesis of the first 125I-labeled radioligands in the field, one of which contains a photoaffinity label which enables it to bind irreversibly to the high-affinity GHB binding sites.

Intramolecular addition of benzylic radicals onto ketenimines. Synthesis of 2-alkylindoles

The inter- and intramolecular addition of free radicals onto ketenimines is studied. All the attempts to add intermolecularly several silicon, oxygen or carbon centered radicals to N-(4-methylphenyl)-C,C-diphenyl ketenimine were unsuccessful. In contrast, the intramolecular addition of benzylic radicals, generated from xanthates, onto the central carbon of a ketenimine function with its N atom linked to the ortho position of the aromatic ring occurred under a variety of reaction conditions. These intramolecular cyclizations provide a novel radical-mediated synthesis of 2-alkylindoles.