65562-84-7

Upstream product

• 98-86-2 acetophenone 
• 5392-40-5 (E/Z)-3,7-dimethyl-2,6-octadienal 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 70-11-1 α-bromoacetophenone 
• 96839-90-6 geranial 

Downstream Products

• 1377807-04-9 C₂₈H₂₈BrNO₃ 
• 65562-86-9 5,9-dimethyl-1-phenyldec-8-en-1-one 
• 65562-94-9 (E)-7,11-Dimethyl-3-phenyl-dodeca-2,10-dienoic acid ethyl ester 
• 65562-90-5 (Z)-7,11-Dimethyl-3-phenyl-dodeca-2,10-dienoic acid ethyl ester 

Relevant academic research and scientific papers

Carbon-Carbon Bond Formation between α-Halogenoketones and Aldehydes Promoted by Cerium(III) Iodide or Cerium(III) Chloride-Sodium Iodide

α-Halogenoketones react with aldehydes to form α,β-unsaturated ketones accompanied by dehalogenation in the presence of cerium(III) iodide, but the use of cerium(III) chloride-sodium iodide results in the formation of β-keto alcohols.

Reaction of α-Halogeno Ketones with Carbonyl Compounds Promoted by CeI3, CeCl3-NaI,or CeCl3-SnCl2

Reaction of α-halogeno ketones with aldehydes in the presence of CeI3 in tetrahydrofuran is found to give α,β-unsaturated ketones in excellent yields under mild conditions.In contrast, treatment of α-halogeno ketones and carbonyl compounds with CeCl3-NaI or CeCl3-SnCl2 affords β-hydroxy ketones in good yields.It is assumed that these reactions proceed via cerium enolates.The combined reagents, however, cannot be applied to a Reformatsky-type reaction.Regiospecific and aldehyde chemoselective aldol synthesis are also described.