65621-26-3

Basic information

• Product Name: Z-DAP(Z)-OH
• Synonyms: N-ALPHA,BETA-BIS-Z-L-2,3-DIAMINOPROPIONIC ACID;N-ALPHA, BETA-DICARBOBENZOXY-L-2,3-DIAMINOPROPIONIC ACID;Z-ALPHA,BETA-DIAMINOPROPIONIC ACID(Z)-OH;Z-DAP(Z)-OH;L-ALANINE, N-[(PHENYLMETHOXY)CARBONYL]-3-[[(PHENYLMETHOXY)CARBONYL]AMINO]-;CBZ-L-DAP(CBZ)-OH;CBZ-L-DpaCBZ-OH;Nα,β-Bis-Z-L-2,3-diaminopropionic acid
• CAS NO: 65621-26-3
• Molecular Formula: C₁₉H₂₀N₂O₆
• Molecular Weight: 372.37
• Mol File: 65621-26-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 627.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.306±0.06 g/cm3(Predicted)
• Storage Temp.: Store at RT.
• PKA: 3.66±0.10(Predicted)
• CAS DataBase Reference: Z-DAP(Z)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-DAP(Z)-OH(65621-26-3)
• EPA Substance Registry System: Z-DAP(Z)-OH(65621-26-3)

Safety Data

• Hazardous Substances Data: 65621-26-3(Hazardous Substances Data)

Usage

Uses

N-alpha,beta-bis-Z-L-2,3-Diaminopropionic Acid

Upstream product

• 1186-65-8 L-2,3-diaminopropionic acid hydrobromide 
• 501-53-1 benzyl chloroformate 
• 60-29-7 diethyl ether 
• 515-94-6 (S)-2,3-diaminopropionic acid 
• 35761-26-3 (S)-3-amino-2-(((benzyloxy)carbonyl)amino)propanoic acid 

Downstream Products

• 65710-57-8 3-{[(benzyloxy)carbonyl]amino}-N-(tert-butoxycarbonyl)-L-alanine 
• 61040-22-0 N^β-benzyloxycarbonyl-N^α-Boc-(S)-β-aminoalanine methyl ester 
• 119140-68-0 (S)-2-{(S)-2-[2-(2,3-Bis-benzyloxycarbonylamino-propionylamino)-acetylamino]-3-phenyl-propionylamino}-4-methyl-pentanoic acid methyl ester 
• 72594-82-2 4(S)-benzyloxycarbonylaminomethyl-2,5-oxazolidinedione 
• 899436-88-5 C₂₁H₂₀N₂O₆ 
• 71749-02-5 N^β-Z-Dap-OMe*HCl 
• 103691-93-6 N-(L-2.3-bis-benzyloxycarbonylamino-propionyl)-glycine ethyl ester 

Relevant articles and documents

Synthesis of (R)- and (S)-2,3-diaminopropyl sulfate: Mechanism based inhibition of glutamate 1-semialdehyde aminomutase

A short synthesis of each enantiomer of 2,3-diaminopropyl hydrogensulfate is described starting from (2R)- and (2S)-asparagine. The compounds serve as inhibitors for pyridoxal 5'-phosphate-dependent (2S)- glutamate 1-semialdehyde aminotransferase, a target for selective herbicides and antibacterial agents on the tetrapyrrole biosynthetic pathway. The (2R)- enantiomer, as predicted, serves as a potent irreversible inactivator. (C) 2000 Elsevier Science Ltd.

AMIDE BOND ISOSTERES: IMIDAZOLINES IN PSEUDOPEPTIDE CHEMISTRY

The 2-imidazole ring has been incorporated as an amide bond replacement into pseudodipeptides, a pseudotripeptide, and pseudopentapeptide enkephalin analogues.