65641-17-0Relevant academic research and scientific papers
A facile one-pot transformation of baylis-hillman adducts into unsymmetrical disubstituted maleimide and maleic anhydride frameworks: A facile synthesis of himanimide A
Basavaiah, Deevi,Devendar, Badugu,Aravindu, Kunche,Veerendhar, Ainelly
supporting information; experimental part, p. 2031 - 2035 (2010/07/05)
Unsymmetrical, disubstituted maleimide and maleic anhydride frameworks have been accessed from Baylis-Hillman adducts in an operationally simple three-step (FriedelCrafts reaction, selective hydrolysis and cyclization), one-pot strategy. This strategy has been successfully extended to the synthesis of a representative bioactive compound, himanimide A (see scheme). (Chemical Equation Representation).
Synthesis of gymnoascolide A
Baag, Md. Merajuddin,Argade, Narshinha P.
, p. 26 - 28 (2008/09/20)
Recently isolated 4-benzyl-3-phenylfuran-2,5-dione and antifungal gymnoascolide A have been synthesized using the chemoselective S N2′ coupling of phenylmagnesium bromide with dimethyl 2-(bromomethyl)fumarate, chemoselective allylic substitution of bromide in 3-(bromomethyl)-4-phenylfuran-2,5-dione with phenylmagnesium bromide and regioselective N-Selectride-induced reduction of 3-benzyl-4-phenylfuran-2,5- dione as the key reactions. Georg Thieme Verlag Stuttgart.
2(3H)- and 2(5H)-furanones. IV. The Di-π-methane rearrangement of 3,4-bis(phenylmethyl)-2(5H)-furanone
Momose,Tanabe,Tsujimori,Muraoka
, p. 2525 - 2530 (2007/10/02)
The photo-irradiation of 3,4-bis(phenylmethyl)-2(5H)-furanone (5) in acetone or in methanol resulted in selective rearrangement of the 4-phenylmethyl moiety and gave 5-phenyl-1-(phenylmethyl)-3-oxabicyclo[3.1.0]hexan-2-one (9) along with cis- and trans-3,
