6566-16-1Relevant academic research and scientific papers
Polyaniline-anchored palladium catalyst-mediated Mizoroki-Heck and Suzuki-Miyauraa reactions and one-pot Wittig-Heck and Wittig-Suzuki reactions
Patel, Heta A.,Patel, Arun L.,Bedekar, Ashutosh V.
, p. 1 - 6 (2015/01/30)
A polyaniline-anchored palladium catalyst was prepared and screened for coupling reactions of aryl halides. The robust and recyclable catalyst was effective in Mizoroki-Heck and Suzuki-Miyaura reactions of aryl bromides and aryl iodides. The catalyst system was further employed for one-pot Wittig-Heck and Wittig-Suzuki combinations to build conjugated compounds in good conversions.
Palladium nanoparticles immobilized on nano-silica triazine dendritic polymer (Pdnp-nSTDP): An efficient and reusable catalyst for suzuki-miyaura cross-coupling and heck reactions
Isfahani, Amir Landarani,Mohammadpoor-Baltork, Iraj,Mirkhani, Valiollah,Khosropour, Ahmad R.,Moghadam, Majid,Tangestaninejad, Shahram,Kia, Reza
supporting information, p. 957 - 972 (2013/05/08)
A new catalyst based on palladium nanoparticles immobilized on nano-silica triazine dendritic polymer (Pdnp-nSTDP) was synthesized and characterized by FT-IR spectroscopy, thermogravimetric analysis, field emission scanning electron microscopy, energy dispersive X-ray, transmission electron microscopy and elemental analysis. The size of the palladium nanoparticles was determined to be 3.1±0.5 nm. This catalytic system showed high activity in the Suzuki-Miyaura cross-coupling of aryl iodides, bromides and chlorides with arylboronic acids and also in the Heck reaction of these aryl halides with styrenes. These reactions were best performed in a dimethylformamide (DMF)/water mixture (1:3) in the presence of only 0.006 mol% and 0.01 mol% of the catalyst, respectively, under conventional conditions and microwave irradiation to afford the desired coupling products in high yields. The Pdnp-nSTDP was also used as an efficient catalyst for the preparation of a series of star- and banana-shaped compounds with a benzene, pyridine, pyrimidine or 1,3,5-triazine unit as the central core. Moreover, the catalyst could be recovered easily and reused several times without any considerable loss of its catalytic activity. Copyright
Inspiration from old dyes: Tris(stilbene) compounds as potent gram-positive antibacterial agents
Boulos, Ramiz A.,Man, Nikki Y. T.,Lengkeek, Nigel A.,Hammer, Katherine A.,Foster, Niki F.,Stemberger, Natalie A.,Skelton, Brian W.,Wong, Pan Yu,Martinac, Boris,Riley, Thomas V.,McKinley, Allan J.,Stewart, Scott G.
, p. 17980 - 17988 (2014/01/17)
Herein we describe the preparation and structure-activity relationship studies on range of stilbene based compounds and their antibacterial activity. Two related compounds, each bearing carboxylic acid moieties, exhibit good activity against several bacterial strains, including methicillin-resistant Staphylococcus aureus MRSA (ATCC 33592 and NCTC 10442). Compound 10 was most active against Moraxella catarrhalis with minimum inhibitory concentrations (MICs) of 0.12-0.25 μg mL-1 and against Staphylococcus spp. with MICs ranging from 2-4 μg mL-1. The derivative 17 showed increased activity with MICs of 0.06-0.25 μg mL-1 against M. catarrhalis and 0.12-1 against Staphylococcus spp. This level of activity is similar to that reported for S. aureus for antibiotics, such as vancomycin, with MICs of ≤2.0 μg mL-1 and clindamycin with MICs of ≤0.5 μg mL -1. As an indicator of toxicity, 17 was tested for its ability to lyse sheep erythrocytes, and showed low haemolytic activity. Such results highlight the value of tris(stilbene) compounds as antibacterial agents providing suitable properties for further development. Routes to new antibiotics: The preparation of and structure-activity relationship studies on a range of stilbene based compounds revealed two related compounds, each bearing carboxylic acid moieties, exhibiting pronounced activity against several bacterial strains including methicillin-resistant Staphylococcus aureus, MRSA (see scheme, dba = dibenzylidene acetone). Copyright
Application of 1-(α-aminobenzyl)-2-naphthols as air-stable ligands for pd-catalyzed Mizoroki-Heck coupling reaction
Chaudhary, Anju R.,Bedekar, Ashutosh V.
experimental part, p. 1778 - 1785 (2012/04/10)
Air-stable, easily accessible Mannich bases, 1-(α-aminobenzyl)-2- naphthols, are used as ligands in palladium-catalyzed Mizoroki-Heck reaction on a variety of substrates. High turnover numbers are observed for both the reactions with aryl bromides and iodides, while aryl chlorides are inert. Copyright Taylor & Francis Group, LLC.
ANTIMICROBIAL COMPOUNDS
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Page/Page column 23, (2013/02/28)
A compound for use as an antimicrobial having a formula (A).
