656830-25-0

Usage

Molecular structure

1H-Pyrrole-2,5-dione core with additional substituents.

3-[4-[(3-methyl-2-butenyl)oxy]phenyl] group

Attached to the 3 position of the pyrrole ring.

4-(2-methylpropyl) group

Attached to the 4 position of the pyrrole ring.

Pharmaceuticals

May have biological activity or serve as an intermediate in drug synthesis.

Materials science

Could be used as a building block for creating new materials with specific properties.

Organic synthesis

May be a valuable intermediate for the synthesis of other complex organic compounds.

Relevance

The specific properties and potential uses of 1H-Pyrrole-2,5-dione, 3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-4-(2-methylpropyl)- depend on its detailed chemical structure and reactivity.

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 106-41-2 4-bromo-phenol 
• 26805-54-9 dimethyl (Z)-2-(bromomethyl)fumarate 
• 656830-26-1 1-hydroxy-3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]-1H-pyrrol-2,5-dione 
• 1411884-68-8 4-isobutyl-3-(4-prenyloxyphenyl)furan-2(5H)-one 
• 1411884-71-3 4-isobutyl-3-(4-prenyloxyphenyl)-2-triisopropylsilyloxyfuran 
• 1030612-07-7 2-hydroxy-3-isobutyl-4-[4-(3-methylbut-2-enyloxy)phenyl]-2H-furan-5-one 
• 358-72-5 dimethylallyl diphosphate 
• 1040394-24-8 3-(4-hydroxyphenyl)-4-isobutyl-1H-pyrrole-2,5-dione 
• 204503-25-3 1-bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene 
• 870-63-3 prenyl bromide 
• 100953-25-1 3-(4-methoxyphenyl)-4-methylfuran-2,5-dione 
• 888223-11-8 3-bromomethyl-4-(4-methoxyphenyl)furan-2,5-dione 
• 847830-10-8 (4-[(3-METHYLBUT-2-EN-1-YL)OXY]PHENYL)BORANEDIOL 

Relevant academic research and scientific papers

Enzymatic O-Prenylation of Diverse Phenolic Compounds by a Permissive O-Prenyltransferase from the Medicinal Mushroom Antrodia camphorata

Prenylated compounds are pharmacologically attractive natural products that are widely distributed in nature. Prenyltransferases (PTs) could catalyze the transfer of prenyl moieties to aromatic acceptors and increase the structural diversity and biological activity of natural products. In this work, a permissive O-prenyltransferase AcaPT was discovered from Antrodia camphorata, a precious medicinal mushroom in Taiwan. AcaPT exhibited robust O-prenylation capability toward structurally diverse drug-like phenolic compounds, including antrodins, flavonoids, and coumarins. In total, 23 O-prenylated products were obtained by scaled-up enzymatic synthesis. AcaPT could be used as an efficient biocatalyst to synthesize O-prenylated derivatives for drug discovery. (Figure presented.).

Unified route to asymmetrically substituted butenolide, maleic anhydride, and maleimide constituents of Antrodia camphorata

The first synthesis of antrocinnamomin D and a new synthesis of antrodins A and B have been achieved in 6-8 steps and high overall efficiency (51, 46, and 43%, respectively) from commercially available methyl 4-hydroxyphenylacetate. Key steps include Fuerstner-Kochi iron-catalyzed sp2-sp 3 cross-coupling and 2-silyloxyfuran oxyfunctionalization.

Compounds isolated from antrodia cinnamomea and use thereof

The present invention relates to novel compounds from Antrodia cinnamomea and their use.

Total synthesis of (±)-camphorataimides and (±)-himanimides by NaBH4/Ni(OAc)2 or Zn/AcOH stereoselective reduction

Maleic anhydride 1 of Antrodia camphorate, which can be isolated from Chinese herbal medicine, is achieved in which the longest linear sequence is only five steps, in 40% overall yield from commercially available succinic anhydride. The crucial antrodimid

A concise synthesis of maleic anhydride and maleimide natural products found in Antrodia camphorata

Recently, the natural products maleic anhydride 1 and maleimides 2 and 3 have been isolated from the mycelium of Antrodia Camphorata, each displaying activity in LLC cell lines. We describe a concise synthesis of each of these natural compounds utilizing C-C cross-coupling methodology, namely, the Negishi and Suzuki reactions. This efficient and high yielding synthesis is convergent lending itself to production of medicinal analogues.

Synthesis of natural cytotoxic camphorataimides B and C

Recently isolated camphorataanhydride A and cytotoxic camphorataimides B and C have been synthesized using chemoselective SN2′ Grignard coupling reaction of p-methoxyphenyl-magnesium bromide with dimethyl bromomethylfumarate and chemoselective

Novel mixture and compounds from mycelia of Antrodia camphorata and use thereof

The present invention relates to novel mixture and maleic and succinic acid derivatives from mycelium of Antrodia Camphorata and the medical use thereof. The present invention relates to the composition or mycelium comprising the compounds of the invention.