656830-26-1Relevant articles and documents
A concise synthesis of maleic anhydride and maleimide natural products found in Antrodia camphorata
Stewart, Scott G.,Polomska, Marta E.,Lim, Rou Wei
, p. 2241 - 2244 (2007/10/03)
Recently, the natural products maleic anhydride 1 and maleimides 2 and 3 have been isolated from the mycelium of Antrodia Camphorata, each displaying activity in LLC cell lines. We describe a concise synthesis of each of these natural compounds utilizing C-C cross-coupling methodology, namely, the Negishi and Suzuki reactions. This efficient and high yielding synthesis is convergent lending itself to production of medicinal analogues.
Synthesis of natural cytotoxic camphorataimides B and C
Baag, Merajuddin,Argade, Narshinha P.
, p. 1005 - 1008 (2007/10/03)
Recently isolated camphorataanhydride A and cytotoxic camphorataimides B and C have been synthesized using chemoselective SN2′ Grignard coupling reaction of p-methoxyphenyl-magnesium bromide with dimethyl bromomethylfumarate and chemoselective