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2-Fluoro-N,N-diMethyl-4-nitroaniline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

65739-04-0

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65739-04-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 65739-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,7,3 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 65739-04:
(7*6)+(6*5)+(5*7)+(4*3)+(3*9)+(2*0)+(1*4)=150
150 % 10 = 0
So 65739-04-0 is a valid CAS Registry Number.

65739-04-0 Well-known Company Product Price

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  • Alfa Aesar

  • (H63930)  2-Fluoro-N,N-dimethyl-4-nitroaniline, 97%   

  • 65739-04-0

  • 250mg

  • 196.0CNY

  • Detail
  • Alfa Aesar

  • (H63930)  2-Fluoro-N,N-dimethyl-4-nitroaniline, 97%   

  • 65739-04-0

  • 1g

  • 588.0CNY

  • Detail
  • Alfa Aesar

  • (H63930)  2-Fluoro-N,N-dimethyl-4-nitroaniline, 97%   

  • 65739-04-0

  • 5g

  • 2352.0CNY

  • Detail

65739-04-0Relevant articles and documents

NOVEL 4,6-DISUBSTITUTED AMINOPYRIMIDINE DERIVATIVES HAVING BOTH AROMATIC AND HALOGENIC SUBSTITUENTS

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Paragraph 0583; 0584, (2014/03/24)

Certain 4,6-disubstituted aminopyrimidine derivatives having both aromatic and halogenic substituents.

Exploratory process development and kilogram-scale synthesis of a novel oxazolidinone antibacterial candidate

Yang, Tao,Chen, Jia-Xiang,Fu, Yiwei,Chen, Kaixiao,He, Jinyun,Ye, Weiwei,Sang, Zitai,Luo, Youfu

, p. 511 - 519 (2014/05/06)

A concise, environmentally benign, and cost-effective route was developed for the large-scale preparation of 1, a novel oxazolidinone antibacterial candidate. The key intermediate 2-(1-(2-fluoro-4-nitrophenyl)-1H-pyrazol-4-yl) pyridine 7 was prepared with high purity by mild deamination of the regioisomeric mixture 21. The mixture was prepared from a nucleophilic SNAr reaction by selective C-N coupling of the secondary amine functionality of 4-(pyridin-2-yl)-1H-pyrazol-3-amine 14 with 1,2-difluoro-4-nitrobenzene 10 in optimized conditions with the primary amine group remaining intact. The gaseous nitrogen release rate and reaction mixture temperature of the deamination step can be well controlled by altering the feeding manner, thereby providing safety guarantees. The optimized synthetic strategy of 1 with an overall yield of 27.6%, including seven sequential transformations by only five solid-liquid isolations, significantly improved the product separation workup. The strategy bypassed time-consuming and laborious procedures for any intermediate involved as well as for the final API. This study presents a process enabling the rapid delivery of a multikilogram quantity of API with high purity.

NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

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Page/Page column 114; 115, (2012/11/14)

The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

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Page/Page column 106, (2012/12/13)

The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

BIFUNCTIONAL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME

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Page/Page column 249, (2010/02/06)

The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional hetercyclic compounds, and methods of using such compounds as anti-infective, anti-proliferative agents, anti-inflammatory, and/or prokinetic agents.

THE PHOTOREACTIONS OF 2-FLUORO-4-NITROANISOLE WITH AMINES. THE SEARCH FOR NEW BIOCHEMICAL PHOTOPROBES

Figueredo, M.,Marquet, J.,Moreno-Manas, M.,Pleixats, R.

, p. 2427 - 2428 (2007/10/02)

The photosubstitutions of 2-fluoro-4-nitroanisole with several amines are studied from the preparative and the preliminary mechanistic points of view.The possible usefulness of this structure as biochemical photoprobe is discussed.

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