65927-22-2

Upstream product

• 124-38-9 carbon dioxide 
• 14092-00-3 methyl o-tolyl sulfide 
• 496-31-1 benzo[b]-2,3-dihydrothiophen-2-one 
• 79099-22-2 2-(2-(ethoxycarbonothioylthio)phenyl)acetic acid 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 
• 79099-23-3 (2-mercaptophenyl)acetic acid disodium salt 
• 79-11-8 chloroacetic acid 
• 39161-85-8 alpha-mercaptophenylacetic acid 
• 79-08-3 bromoacetic acid 

Downstream Products

• 18926-44-8 ethyl 2-(ethoxycarbonylmethylthio)phenylethanoate 
• 81549-22-6 4-benzoylthiochroman-3-one 
• 81549-24-8 2-phenyl-2H-1-benzothiopyran-S,S-dioxide 
• 81549-23-7 3,4-dihydro-3-hydroxy-3-phenyl-2H-1-benzothiopyran 
• 53844-17-0 3-phenyl-2H-1-benzoyhiopyran 
• 145430-40-6 3-Phenyl-3H,5H-thiopyrano<2,3-c><1>benzothiopyran-2-carbaldehyde 
• 16895-58-2 2H-1-benzothiopyran-3(4H)-one 

Relevant academic research and scientific papers

Enamino Ketones as Precursors of Functionalised 2H-Thiopyrans and Thiopyrano- and -benzothiopyrans

Oxo enamino ketones obtained by treating active methylene compounds with N,N-dimethylformamide dimethyl acetal yield novel 2H-thiopyrans in a regioselective one pot thionation--cycloaddition sequence.Application of similar methodology to thiochroman-3-ones affords novel thiopyranobenzothiopyrans and the isomers.

Metalation reactions XIII. The reactions of electrophiles with the dilithiated species 1-(α-lithiomethyl)-2-benzene

Direct dimetalation of 1-methyl-2-(methylthio)benzene (1) gives the dilithiated species (2) in good yield, which can be used to introduce substituents into the thiomethyl and methyl groups.Species 2 can react also with a variety of dichlorosilanes and dichlorostannanes, and with sulphur chloride, to yield derivatives of 1,3-benzothiasilin, 1,3-benzothiastannin and 1,3-benzodithiin respectively.Reaction of 2 with tetrachlorosilane yields a spirocyclic silicon compound, while reaction with benzoyl chloride yields a derivative of 1-benzothiopyran.

The preparation of some thiochroman-3-ones and derivatives

The use of 2,3-dihydrobenzothiophene-2,3-dione as a source of 2-mercaptophenylacetic acid permits a convenient preparation of 2-carboxymethylthiophenylacetic acid or derivatives.These undergo a Dieckmann cyclization to 3-acetoxybenzothiopyrans, which m

A Synthesis of the 2H-Benzothiocin System through Cycloaddition

Thiochroman-3-one has been prepared from o-nitrophenylacetic acid.Cycloaddition of dimethyl acetylenedicarboxylate to the pyrrolidine enamine of thiochroman-3-one, followed by electrocyclic ring opening of the cyclobutene system in the tricyclic adduct, y