65956-64-1Relevant academic research and scientific papers
Cationic amphiphiles of methylphosphonates and cholesterol phosphocholines and their homo derivatives
Predvoditelev,Malenkovskaya,Nifant'ev
, p. 1530 - 1534 (2003)
A method of synthesis of (P → O) and (P → N)-choline cholesteryl methylphosphonates and their homo derivatives of the cationic type is developed. These compounds were obtained by the Arbuzov reaction between bromomethane and cyclic cholesteryl phosphorous esters and amidoesters and subsequent aminolysis of the intermediate bromoalkyl phosphonates. Alkylation of trimethylamine with cholesteryl ethanediyl and propanediyl phosphates gives cholesterol phosphocholines and their homo derivatives.
SYNTHESIS OF PHOSPHORIC ESTERS
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Page/Page column 5-6, (2012/09/05)
The present invention relates to a process for the preparation of phosphoric esters, and to selected compounds.
