659730-49-1Relevant academic research and scientific papers
Chemoselective chromium(II)-catalyzed cross-coupling reactions of dichlorinated heteroaromatics with functionalized aryl Grignard reagents
Steib, Andreas K.,Kuzmina, Olesya M.,Fernandez, Sarah,Malhotra, Sushant,Knochel, Paul
supporting information, p. 1961 - 1965 (2015/01/30)
Chromium(II) chloride catalyzes the chemoselective cross-coupling reaction of dichloropyridines with a range of functionalized (hetero)aromatic Grignard reagents at room temperature. Functional groups, such as esters and acetals, are well tolerated in this transformation. Previously challenging substrates, quinolines and isoquinolines, participate in the selective Cr-catalyzed cross-coupling in cyclopentyl methyl ether (CPME) as the solvent. The effective purging of Cr salts is demonstrated by using various solid supports.
NOVEL HETEROCYCLIC COMPOUNDS AS ANTIMALARIAL AGENTS
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Page/Page column 87, (2015/03/16)
The invention relates to novel heterocyclic compounds of the Formula I. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of the Formula I and
2-PHENYL-6-AZOLYLPYRIDINE-BASED LIGAND AND GROUP VIII TRANSITION METAL COMPLEX
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Paragraph 0092; 0093, (2013/03/26)
A 2-phenyl-6-azolylpyridine-based ligand is represented by the following formula (I): wherein, X represents nitrogen or C—R10; R1, R2, R3, R4, R5, R6, R7, R8 /su
TBAF-Catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: Access to arylpyridines and bihetaryl compounds
Louerat, Frederic,Tye, Heather,Napier, Spencer,Garrigou, Michael,Whittaker, Mark,Gros, Philippe C.
supporting information; experimental part, p. 1768 - 1773 (2011/04/26)
The concomitant use of silver oxide and catalytic amount of TBAF allowed the efficient and chemoselective coupling of readily available 4-chloro- and 4-methyl-2-trimethyl-silyl-pyridines with heteroaromatic and aromatic halides. Based on control experiments, a mechanism involving the formation of a pyridylsilver intermediate and TBAF recycling is postulated.
VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS
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Page/Page column 92, (2010/02/11)
Compounds having the general structure formula (I) and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tensi
