66016-19-1

Basic information

• Product Name: 3-Pentylcyclobutanecarboxylic acid
• Synonyms: 3-Pentylcyclobutanecarboxylic acid
• CAS NO: 66016-19-1
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.2487
• Mol File: 66016-19-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 266.3°Cat760mmHg
• Flash Point: 127.9°C
• Appearance: /
• Density: 0.999g/cm³
• Vapor Pressure: 0.00251mmHg at 25°C
• Refractive Index: 1.473
• PKA: 4.83±0.40(Predicted)
• CAS DataBase Reference: 3-Pentylcyclobutanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentylcyclobutanecarboxylic acid(66016-19-1)
• EPA Substance Registry System: 3-Pentylcyclobutanecarboxylic acid(66016-19-1)

Safety Data

• Hazardous Substances Data: 66016-19-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H18O2/c1-2-3-4-5-8-6-9(7-8)10(11)12/h8-9H,2-7H2,1H3,(H,11,12)

Upstream product

• 6065-59-4 diethyl n-pentylmalonate 
• 105-53-3 diethyl malonate 
• 66016-04-4 3-Pentyl-cyclobutane-1,1-dicarboxylic acid diethyl ester 
• 110-53-2 1-Bromopentane 
• 497-19-8 sodium carbonate 
• 111241-42-0 2-pentylpropane-1,3-diyl bis(4-methylbenzenesulfonate) 
• 25462-23-1 2-pentylpropane-1,3-diol 

Downstream Products

• 127113-77-3 Toluene-4-sulfonic acid 3-pentyl-cyclobutylmethyl ester 

Relevant articles and documents

CYCLOALKYL-CONTAINING CARBOXYLIC ACIDS AND USES THEREOF

The present application discloses a compound of formula (I) or a salt thereof: (I) and compositions comprising such compound or salt thereof. The use of such compound, salt thereof or composition comprising same for treating anemia or leukopenia, fibrosis, cancer, hypertension and/or a metabolic condition in a subject is also disclosed.

Synthesis and Liquid Crystal Properties of Dimethylene Linked Compounds Incorporating the Cyclobutane or Spiroheptane Rings

The preparation of sixteen dimethylene linked compounds is described heptane ring>, and a comparison is made between the transition temperatures of these compounds and those of the corresponding esters.This comparison once again highlights the fact that the cyclobutane ring should be regarded, in terms of its ability to promote nematic thermal stability, as a "chain stiffener rather than as a ring system.A comparison is also made of the nematic thermal stabilities of the trans-cyclobutane and the spiroheptane systems and of the trans-cyclohexane and the spiroundecane systems.

Research on cyclobutane compounds of biological interest. III. Syntheses and structure activity (antiinflammatory and antalgic) relationships of 3-substituted cyclobutane carboxylic acids

Antiinflammatory and analgesic activities of 3 substituted cyclobutanecarboxylic acids are pointed out and their structure-activity relationship examined according to the Hansch method. This analysis shows the influence of the steric and lipophilic parameters and this quantitative basis let us realize the synthesis of two acids, the analgesic acitivities of which are very much improved. Attempted quantitative correlations between physiochemical parameters and antiinflammatory activity were unsuccessful. This is imputable to a too imprecise representation of the steric effect which plays a primordial part in this kind of activity.