6610-16-8Relevant articles and documents
Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene
Roiban, Gheorghe-Doru,Agudo, Rubén,Reetz, Manfred T.
, p. 5306 - 5311 (2013/07/05)
The selective partial oxidation of small non-functionalized molecules using biocatalysis based on P450 monooxygenases is known to be difficult due to the expected poor regio- and stereoselectivity, but in this study it was nevertheless attempted. 1-Methyl
A [3,3]-sigmatropic process catalysed by acetate. The decarboxylative Claisen rearrangement
Bourgeois, Damien,Craig, Donald,Grellepois, Fabienne,Mountford, David M.,Stewart, Alan J. W.
, p. 483 - 495 (2007/10/03)
Allylic tosylacetates and tosylmalonates undergo acetate-catalysed decarboxylative Claisen rearrangement in the presence of N,O-bis(trimethylsilyl) acetamide. The homoallylic sulfones formed in these transformations correspond to the products of regiospecific allylation of sulfone-stabilised carbanions. A mechanistic rationale is proposed.
A new system for catalytic enantioselective reduction of achiral ketones to chiral alcohols. Synthesis of chiral α-hydroxy acids
Corey,Bakshi
, p. 611 - 614 (2007/10/02)
The reduction of a variety of achiral ketones with catecholborane as stoichiometric reductant and 0.1 equiv of oxazaborolidine 2 as catalyst in toluene at -78°C proceeds in > 95% yield and with enantioselectivities in the range 30:1 to 9:1, depending on s