66102-65-6Relevant academic research and scientific papers
The synthesis of pyrroles and oxazoles based on gold α-imino carbene complexes
Loy, Nicole S. Y.,Choi, Subin,Kim, Sunggak,Park, Cheol-Min
, p. 7336 - 7339 (2016)
Cationic gold complexes of α-oximimino carbenes have been identified to react with weak nucleophiles including enol ethers and nitriles. These findings allowed us to develop the highly efficient synthesis of pyrroles and oxazoles.
Synthesis of unsymmetrical pyrazines based on ?±-diazo oxime ethers
Loy, Nicole S. Y.,Kim, Sunggak,Park, Cheol-Min
supporting information, p. 395 - 397 (2015/03/03)
Synthesis of unsymmetrically substituted pyrazines has been a challenge. The reactivity of ?±-imino carbenoids derived from ?±-diazo oxime ethers has been exploited for pyrazine synthesis, in which the reaction of ?±-diazo oxime ethers with 2H-azirines provides highly substituted pyrazines in good to excellent yields.
Facile synthesis of 2-alkyl/aryloxy-2H-azirines and their application in the synthesis of pyrroles
Qi, Xinxin,Xu, Xianxiu,Park, Cheol-Min
supporting information; experimental part, p. 3996 - 3998 (2012/06/04)
Free carbenes generated from α-diazo oxime ethers by photolysis undergo facile N-O insertion to afford 2-alkyl/aryloxy-2H-azirines in good to excellent yields. This method allowed for the development of a tandem reaction for pyrrole synthesis via 1,3-dipolar cycloaddition.
