66102-65-6

Basic information

• Product Name: trans-ethyl 3-(methoxyimino)-3-phenylpropanoate
• Synonyms: trans-ethyl 3-(methoxyimino)-3-phenylpropanoate
• CAS NO: 66102-65-6
• Molecular Weight: 221.256
• Mol File: 66102-65-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: trans-ethyl 3-(methoxyimino)-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: trans-ethyl 3-(methoxyimino)-3-phenylpropanoate(66102-65-6)
• EPA Substance Registry System: trans-ethyl 3-(methoxyimino)-3-phenylpropanoate(66102-65-6)

Safety Data

• Hazardous Substances Data: 66102-65-6(Hazardous Substances Data)

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 1372793-96-8 (Z)-ethyl 2-diazo-3-(methoxyimino)-3-phenylpropanoate 
• 38597-58-9 2-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 65474-26-2 ethyl 2,5-diphenyl-1H-pyrrole-3-carboxylate 

Relevant articles and documents

The synthesis of pyrroles and oxazoles based on gold α-imino carbene complexes

Cationic gold complexes of α-oximimino carbenes have been identified to react with weak nucleophiles including enol ethers and nitriles. These findings allowed us to develop the highly efficient synthesis of pyrroles and oxazoles.

Facile synthesis of 2-alkyl/aryloxy-2H-azirines and their application in the synthesis of pyrroles

Free carbenes generated from α-diazo oxime ethers by photolysis undergo facile N-O insertion to afford 2-alkyl/aryloxy-2H-azirines in good to excellent yields. This method allowed for the development of a tandem reaction for pyrrole synthesis via 1,3-dipolar cycloaddition.