6629-80-7

Basic information

• Product Name: 4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-phenyl-
• Synonyms: 4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-phenyl-;2-phenyl-2,3-dihydro-1,3-benzoxazin-4-one
• CAS NO: 6629-80-7
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.24
• Mol File: 6629-80-7.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 483.2°C at 760 mmHg
• Flash Point: 246°C
• Appearance: /
• Density: 1.223g/cm³
• Vapor Pressure: 1.72E-09mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: 4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-phenyl-(6629-80-7)
• EPA Substance Registry System: 4H-1,3-Benzoxazin-4-one, 2,3-dihydro-2-phenyl-(6629-80-7)

Safety Data

• Hazardous Substances Data: 6629-80-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H11NO2/c16-13-11-8-4-5-9-12(11)17-14(15-13)10-6-2-1-3-7-10/h1-9,14H,(H,15,16)

Upstream product

• 100-52-7 benzaldehyde 
• 65-45-2 salicylamide 
• 100-39-0 benzyl bromide 
• 21725-69-9 3-hydroxybenzisoxazole 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 90-02-8 salicylaldehyde 
• 55424-93-6 2-phenyl-4-oxo-1,3-benzoxazine perchlorate 

Downstream Products

• 94623-58-2 N-benzhydryl-salicylamide 
• 100-52-7 benzaldehyde 
• 65-45-2 salicylamide 
• 538-51-2 benzylidene phenylamine 
• 101090-00-0 2-Hydroxy-benzoesaeure-<1-phenyl-aethylamid> 
• 6329-74-4 5-bromo-2-hydroxybenzamide 
• 872988-86-8 4-[2-(2-phenyl-4-oxo-3,4-dihydro-2H-benzo[1,3]oxazin-3-yl)ethoxy]benzaldehyde 
• 30566-92-8 5-(N,N-dibenzylamino)acetylsalicylamide 
• 152675-28-0 N-(2-phenyl-3,4-dihydro-4-oxoquinazolin-3-yl)chloroacetamide 
• 1904-60-5 3-amino-2-phenylquinazolin-4(3H)-one 
• 1228146-48-2 C₂₄H₁₇N₅O₃S 
• 1228146-45-9 N-(4-oxo-2-phenylquinazolin-3(4H)-yl)-2-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide 
• 102549-30-4 2-acetoxy-benzoic acid benzhydrylamide 
• 5663-74-1 N-benzoylsalicylamide 

Relevant articles and documents

Synthesis of C(2)halomethyl substituted derivatives of 2,3-dihydro-1,3-benzoxaz-4-ones

-

Synthesis and anticonvulsant activity evaluation of 2-Phenyl-2H-benzo[e][1, 3]oxazin-4(3H)-ones

A series of new 2-phenyl-2H-benzo[e][1,3]oxazin-4(3H)-one derivatives (1a-1t) were designed based on the known anticonvulsant activity of quinolinone derivatives. All target compounds 1a-1t, characterized by IR, 1H NMR and MS, have been evaluated for their anticonvulsant activity against MES-induced seizures. The pharmacological results showed that all the compounds displayed some degree of anticonvulsant activity. Among them, 2-phenyl-2,3-dihydrobenzo[e][1,3]oxazin-4-one (1a) and 2-(2-fluorophenyl)-2,3- dihydrobenzo-[e][1,3]oxazin-4- one (1b) were considerd more promising because of their lower ED50 (34.1 and 28.4 mg/kg) and higher protective index (11.1 and 8.0).

One-pot heterocondensation for benzoxazinone derivatives using sodium perborate as catalsyt

An efficient synthesis of series of benzoxazinones, employing sodium perborate tetrahydrate (SPB) as a condensing agent is described. SPB in water and formic acid system is proved as a selective catalyst of hydration for cyanides. The rate enhancement and